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MetabolomicsReactive Oxygen Species Deficiency Due to Ncf1-Mutation Leads to Development of Adenocarcinoma and Metabolomic and Lipidomic Remodeling in a New Mouse Model of Dextran Sulfate Sodium-Induced Colitis
Inflammatory bowel disease is characterized by chronic relapsing idiopathic inflammation of the gastrointestinal tract and persistent inflammation. Studies focusing on the immune-regulatory function of reactive oxygen species (ROS) are still largely missing. In this study, we analyzed an ROS-deficie...
2019-05-22 | MTBLS593 | MetaboLights
UnknownConformational landscape of multidomain SMAD proteins.
Not available
S-EPMC8479633 | biostudies-literature
UnknownDynamic ensembles of SARS-CoV-2 N-protein reveal head-to-head coiled-coil-driven oligomerization and phase separation.
Not available
S-EPMC12159747 | biostudies-literature
UnknownClick-Derived Triazoles and Triazolylidenes of Manganese for Electrocatalytic Reduction of CO2.
Not available
S-EPMC8588546 | biostudies-literature
UnknownMicrowave-Assisted Digestion Method and Dispersive Magnetic Solid-Phase Microextraction for the Determination of Major and Trace Elements in Lignocellulosic Biomass by ICP-OES.
Not available
S-EPMC12290956 | biostudies-literature
UnknownUnveiling the dimer/monomer propensities of Smad MH1-DNA complexes.
Not available
S-EPMC7810915 | biostudies-literature
ProteomicsMicroenvironment remodeling during human iPSC-derived NSC 3D differentiation
Brain microenvironment plays an important role in neurodevelopment and function, where extracellular matrix (ECM) components and soluble factors modulate cellular features, as migration, proliferation survival and neuronal function. Disruption of microenvironment’s homeostasis is often related to pa...
ORGANISM(S): Homo sapiens (Human) 
2018-07-31 | PXD007130 | Pride
3d cultures  neual differentiation  hipsc-derived nsc  ecm  microenvironment  swath 
ProteomicsAddressing human astrogliosis in a hiPSC-derived 3D CNS model
Astrogliosis is an inflammatory process by which astrocytes undergo morphological, transcriptional, and functional changes that primarily contribute to tissue healing and restore CNS homeostasis as a response to neuroinflammation. However, excessive astrocyte activation causes neuronal death, immune...
ORGANISM(S): Homo sapiens (Human) 
2025-07-28 | PXD043835 | Pride
Astrogliosis  neuroinflammation  hipsc  3d culture  reactive astrocytes  stirred-tank bioreactors 
TranscriptomicsThe Complete Genome of a Single Individual by Massively Parallel DNA Sequencing
The association of genetic variation with disease and drug response, together with improvements in nucleic acids technologies, has given great optimism for the impact of 'genomic medicine'. However, the formidable size of the diploid human genome has prevented the routine application of sequencing ...
ORGANISM(S): Homo sapiens 
2010-05-26 | E-GEOD-10668 | biostudies-arrayexpress
ProteomicsTime-dependent proteomic signatures associated with embry-ogenic callus induction in Carica papaya L.
The cost of Carica papaya production through seed-based propagation is increased by sex segregation, making in vitro techniques a more appealing option for clonal propagation. Inducing embryogenic callus with 2,4-dichlorophenoxyacetic acid (2,4-D) hold the potential to large-scale cloning, although ...
ORGANISM(S): Carica papaya 
2024-01-26 | PXD046521 | Pride
Bottom-up proteomics  carica papaya  embryogenic callus  somatic embryos  time-series analysis. 
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