The emergence, organization, and persistence of cellular life are the result of the functional integration of metabolic and genetic networks. Here, we engineer phospholipid vesicles that can operate three essential functions, namely transcription-translation of a partial genome, self-replication ...
This model is from the article:
Workflow for generating competing hypothesis from models with parameter uncertainty.
David Gomez-Cabrero, Albert Compte and Jesper Tegner Interface Focus
6 June 2011 vol. 1 no. 3 438-449;
doi: 10.1098/rsfs.2...
Cathepsin A (CTSA) is a lysosomal carboxypeptidase present at the cell surface and secreted outside the cell. Additionally, CTSA binds to β-galactosidase and neuraminidase 1 to protect them from degradation. CTSA has gained attention as a drug target for the treatment of cardiac hypertrophy and hear...
A data-entrained computational model for
testing the regulatory logic of the vertebrate unfolded protein
response
This model is described in the article:
A data-entrained
computational model for testing the regulatory logic of the
vertebrate unfolded...
LET-418/Mi-2 is an ATP-dependent chromatin remodeler and is part of large complexes like the NuRD complex which are repressive complex and has a role in vulval development in Caenorhabditis elegans. Along with MEP-1, LET-418 also forms the MEC complex which functions in the post embryonic developmen...
