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TranscriptomicsFailures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun
After nerve injury, myelin and Remak Schwann cells reprogram to repair cells specialized for regeneration. Normally providing strong regenerative support, these cells fail in aging animals, and during the chronic denervation that results from slow axon growth. This impairs axonal regeneration and ca...
ORGANISM(S): Mus musculus 
2020-10-14 | E-MTAB-9640 | biostudies-arrayexpress
TranscriptomicsExpression data from Saccharomyces cerevisiae strains deleted for the THSC/TREX-2 subunits Thp1, Sac3 and Sus1
Transcription is a major obstacle for replication fork progression and a cause of genome instability. Such instability increases in mutants with a suboptimal assembly of the nascent messenger ribonucleo-protein particle (mRNP), as THO/TREX and the NPC-associated THSC/TREX-2 complex. We used microarr...
ORGANISM(S): Saccharomyces cerevisiae 
2014-10-08 | E-GEOD-56702 | biostudies-arrayexpress
UnknownPrediction of week 4 virological response in hepatitis C for making decision on triple therapy: the Optim study.
Not available
S-EPMC4426774 | biostudies-literature
UnknownUnusual isolation of Pseudoglutamicibacter cumminsii in urine culture.
Not available
S-EPMC8790646 | biostudies-literature
UnknownMyroides odoratus as an unusual urinary tract infection pathogen in immunosuppressed patient.
Not available
S-EPMC9728597 | biostudies-literature
UnknownComprehensive genomic diagnosis of non-syndromic and syndromic hereditary hearing loss in Spanish patients.
Not available
S-EPMC6038346 | biostudies-literature
UnknownCisplatin Eligibility Issues and Alternative Regimens in Locoregionally Advanced Head and Neck Cancer: Recommendations for Clinical Practice.
Not available
S-EPMC6579895 | biostudies-literature
TranscriptomicsThe HDAC inhibitor panobinostat (LBH589) inhibits Acute Lymphoblastic leukemia (ALL) in vitro and in vivo in a new characterized human ALL mice model (TOM-1 and MOLT-4)
Histone deacetylases (HDACs) have been identified as therapeutic targets due to regulatory function in DNA structure and organization. We have analyzed the role of the LBH589, a novel pan inhibitor of class I and II HDACs, in Acute Lymphoblastic Leukemia. In vitro, LBH589 was shown to induce a dose...
ORGANISM(S): Homo sapiens 
2012-04-17 | E-GEOD-26790 | biostudies-arrayexpress
UnknownMelatonin Reduces NLRP3 Inflammasome Activation by Increasing α7 nAChR-Mediated Autophagic Flux.
Not available
S-EPMC7767051 | biostudies-literature
UnknownSofosbuvir improves HCV-induced insulin resistance by blocking IRS1 degradation.
Not available
S-EPMC7810262 | biostudies-literature
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