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TranscriptomicsInterleukin-1- and Type I Interferon-Dependent Enhanced Immunogenicity of an NYVAC-HIV-1 Env-Gag-Pol-Nef Vaccine Vector with Dual Deletions of Type I and Type II Interferon-Binding Proteins
NYVAC, a highly attenuated, replication-restricted poxvirus, is a safe and immunogenic vaccine vector. Deletion of immune evasion genes from the poxvirus genome is an attractive strategy for improving the immunogenic properties of poxviruses. Using systems biology approaches, we describe herein the ...
ORGANISM(S): Homo sapiens 
2015-01-30 | E-GEOD-65412 | biostudies-arrayexpress
TranscriptomicsImproved Innate and Adaptive Immunostimulation by Genetically Modified HIV-1 Protein Expressing NYVAC Vectors
Attenuated poxviruses are safe and capable to express foreign antigens. Poxviruses are applied in veterinary vaccination and explored as candidate vaccines for humans. However, poxviruses express multiple genes encoding proteins that interfere with components of the innate and adaptive immune respon...
ORGANISM(S): Homo sapiens 
2010-12-21 | E-GEOD-26239 | biostudies-arrayexpress
TranscriptomicsFunctional genomics of human bronchial epithelial cells interacting with conidiospores of Aspergillus fumigatus
The cells of the airway epithelium play critical roles in host defense to inhaled irritants, and in asthma pathogenesis. These cells are constantly exposed to conidiospores of the ubiquitous mould Aspergillus fumigatus, which are small enough to reach the alveoli. This exposure is asymptomatic in mo...
ORGANISM(S): Homo sapiens 
2011-06-01 | E-GEOD-16628 | biostudies-arrayexpress
TranscriptomicsFunctional genomics of Aspergillus fumigatus conidiospores interacting with human bronchial epithelial cells
The cells of the airway epithelium play critical roles in host defense to inhaled irritants, and in asthma pathogenesis. These cells are constantly exposed to conidiospores of the ubiquitous mould Aspergillus fumigatus, which are small enough to reach the alveoli. This exposure is asymptomatic in mo...
ORGANISM(S): Aspergillus fumigatus 
2011-06-01 | E-GEOD-16630 | biostudies-arrayexpress
TranscriptomicsTranscriptomic analysis of interactions between Aspergillus fumigatus conidiospores and human bronchial epithelial cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Aspergillus fumigatus 
2011-06-01 | E-GEOD-16637 | biostudies-arrayexpress
TranscriptomicsTranscriptional profiling of Lung H1299-BRG1 inducible cells
Global Transcriptional analysis of BRG1 in lung cancer cells Comparative transcriptional profile comparing the expression in lung cancer cells before and after restoring the wild type BRG1 or mutant BRG1 expression controlled by the Tet-ON system (doxycycline depending expression)
ORGANISM(S): Homo sapiens 
2012-03-12 | E-GEOD-35168 | biostudies-arrayexpress
UnknownL-A-lus, a new variant of the L-A totivirus found in wine yeasts with Klus killer toxin-encoding Mlus double-stranded RNA: possible role of killer toxin-encoding satellite RNAs in the evolution of their helper viruses.
Not available
S-EPMC3719527 | biostudies-literature
UnknownCharacterization of full-length HIV-1 CRF17_BF genomes and comparison to the prototype CRF12_BF strains.
Not available
S-EPMC3471996 | biostudies-literature
UnknownMIR retrotransposon sequences provide insulators to the human genome.
Not available
S-EPMC4538669 | biostudies-literature
TranscriptomicsExpression profiling of rainbow trout testicular development and spermatogenesis
Trout spermatogenesis proceeds seasonally in a way that all morphological and cellular events tend to be synchronized. We thus used gonads at key stages of the male reproductive cycle together with isolated germ cell populations to study the changes in gene expression underlying testis development. ...
ORGANISM(S): Oncorhynchus mykiss 
2010-05-06 | E-GEOD-16029 | biostudies-arrayexpress
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