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GenomicsGrhl3 is essential for epidermal barrier repair from both physical and immune injury, relevance to lesional skin disease
Epidermal barrier repair mechanisms activated in psoriasis lesions are likely involved in limiting the severity of this disease. We show that loss of grainyhead-like 3 (Grhl3), a pro-terminal differentiation factor in the epidermis, is sufficient to trigger greater sensitivity to and delayed resolut...
ORGANISM(S): Mus musculus 
2014-09-01 | E-GEOD-52648 | biostudies-arrayexpress
TranscriptomicsGene expression in 2,3-Pentanedione Induced Bronchiolitis Oblliterans
Fibrotic and nonfibrotic bronchial tissues were collected from lungs of pentandione exposed rats by laser capture microdissection. Analogous tissue was collected from air-exposed controls. Miroarray analysis revealed a number of DEGs Male Wistar Han rats were exposed to either air or 200 ppm 2,3-pen...
ORGANISM(S): Rattus norvegicus 
2015-03-03 | E-GEOD-52761 | biostudies-arrayexpress
UnknownWhole-genome sequencing reveals host factors underlying critical COVID-19.
Not available
S-EPMC9259496 | biostudies-literature
UnknownMulti-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation.
Not available
S-EPMC9179018 | biostudies-literature
UnknownGenetic drivers of heterogeneity in type 2 diabetes pathophysiology.
Not available
S-EPMC10937372 | biostudies-literature
UnknownAnalysis of shared heritability in common disorders of the brain.
Not available
S-EPMC6097237 | biostudies-literature
UnknownMulti-ancestry genome-wide study in >2.5 million individuals reveals heterogeneity in mechanistic pathways of type 2 diabetes and complications.
Not available
S-EPMC10081410 | biostudies-literature
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