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TranscriptomicsDifferential gene expression in CNS after scrapie infection
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), which are invariably fatalM- neurodegenerative diseases of the central nervous system (CNS). Accumulation of the misfolded prion protein, PrPSc in the CNS results in progressive neurodegenerative disease. Susceptible VRQ homozygous Ne...
ORGANISM(S): Ovis aries 
2014-06-01 | E-MTAB-2369 | biostudies-arrayexpress
TranscriptomicsDifferential gene expression in CNS after scrapie infection 2
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), which are invariably fatal neurodegenerative diseases of the central nervous system (CNS). Accumulation of the misfolded prion protein, PrPSc in the CNS results in progressive neurodegenerative disease. Susceptible VRQ homozygous New ...
ORGANISM(S): Ovis aries 
2014-06-01 | E-MTAB-2385 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of peripheral lymphoid tissue immediately before and after the detection of PrPSc in sheep scrapie 2
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), which are invariably fatal neurodegenerative diseases of the central nervous system (CNS). Accumulation of the misfolded prion protein, PrPSc in the CNS results in progressive neurodegenerative disease. For many transmissible spongif...
ORGANISM(S): Ovis aries 
2014-04-06 | E-MTAB-2330 | biostudies-arrayexpress
TranscriptomicsTranscriptome analysis of peripheral lymphoid tissue immediately before and after the detection of PrPSc in sheep scrapie
Sheep scrapie is a transmissible spongiform encephalopathy (TSE), which are invariably fatal neurodegenerative diseases of the central nervous system (CNS). Accumulation of the misfolded prion protein, PrPSc in the CNS results in progressive neurodegenerative disease. For many transmissible spongif...
ORGANISM(S): Ovis aries 
2014-02-20 | E-MTAB-2327 | biostudies-arrayexpress
TranscriptomicsGastric lymph node responses to T. circumcincta infection.
The aim of the current study is to identify genes that show differential expression within the gastric lymph node of parasite resistant and susceptible sheep. For this we exploited parasite-naïve Blackface lambs with diversity in their predicted genetic resistance to T. circumcincta, which were tric...
ORGANISM(S): Ovis aries 
2013-05-30 | E-MTAB-1580 | biostudies-arrayexpress
TranscriptomicsRNA-seq of the ileo-caecal valve lymph node of sheep with paratuberculosis compared to uninfected controls
Sheep total RNA was extracted from the Ileo-caecal valve lymph node (ICLN) of sheep with multibacillary paratuberculosis compared to ICLN of uninfected controls. Sequencing libaries were prepared from RNA using the Illumina TruSeq RNA Sample Preparation Kit v2. Sequencing with 101 base paired end re...
ORGANISM(S): Ovis aries 
2017-05-03 | E-MTAB-5146 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Ovis aries Iymph node and spleen from animals infected by brain homogenate.
Spleen samples from five sheep (3 diseased and 2 control) were used on 10 chips.
Lymph node samples from five sheep (3 diseased and 2 control) were used on 10 chips.
ORGANISM(S): Ovis aries 
2010-04-01 | E-MEXP-2565 | biostudies-arrayexpress
TranscriptomicsSmall RNA profiling of sheep ICLN from MAP infected and uninfected animals
This study investigated the miRNA profiles of the ICLN from sheep with paratuberculosis or uninfected controls, using Illumina TruSeq Small RNA sequencing.
ORGANISM(S): Ovis aries 
2019-01-01 | E-MTAB-5744 | biostudies-arrayexpress
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