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The aim of our work was the comparison of human and mouse gene expression data and to identify a conserved breast tumor gene set. The results encourage the usefulness of transgenic mice as a model for human breast cancer formation and therapy. Keywords: Comparison of gene expression data The aim of ...
ORGANISM(S): Homo sapiens 
Microarray studies revealed that as a first hit, SV40 T/t-antigen causes deregulation of 462 genes in mammary gland cells (ME-cells) of WAP-SVT/t transgenic animals. The majority of deregulated genes are cell-proliferation specific and Rb-E2F dependent, causing ME-cell proliferation and gland hyperp...
ORGANISM(S): Mus musculus 
This SuperSeries is composed of the following subset Series:; GSE6581: Expression data from mammary glands of transgenic mice; GSE6596: Comparison of gene expression data from human and mouse breast cancers: Identification of conserved breast tumor genes Experiment Overall Design: Refer to individua...
ORGANISM(S): Homo sapiens 
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