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ProteomicsAn Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens
There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2020-02-04 | MSV000084899 | MassIVE
GenomicsDevelopment and Characterization of Bacteriophage Cocktails targeting Gram-Negative ESKAPE Pathogens
Development and Characterization of Bacteriophage Cocktails targeting Gram-Negative ESKAPE Pathogens
PRJEB123093 | ENA
ProteomicsAn Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens
There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-...
ORGANISM(S): Escherichia coli 
2019-10-22 | PXD010174 | Pride
Macrocyclic peptidomimetic antibiotics Novel molecular mode of action Lpt complex E.coli Dda Ompta (outer membrane-targeting antibiotics) Lc-ms/ms Bam complex Photoaffinity labeling Thermo q-exactive plus Interaction mapping Photo crosslinking Gram-negative eskape pathogens 
GenomicsAlternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens
Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens
PRJNA1154271 | ENA
TranscriptomicsAlternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens
Acinetobacter baumannii is an ESKAPE pathogen that rapidly develops resistance to antibiotics and persists for extended periods in the host or on abiotic surfaces. Survival in environmental stress such as phosphate scarcity, represents a clinically significant challenge for nosocomial pathogens. In ...
ORGANISM(S): Acinetobacter baumannii 
2024-10-02 | GSE276010 | GEO
UnknownFluoroamphiphilic polymers exterminate multidrug-resistant Gram-negative ESKAPE pathogens while attenuating drug resistance.
Not available
S-EPMC11352906 | biostudies-literature
UnknownAlternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens.
Not available
S-EPMC11828411 | biostudies-literature
UnknownAlternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens.
Not available
S-EPMC11419095 | biostudies-literature
UnknownStructural Modification of Lipopolysaccharide Conferred by mcr-1 in Gram-Negative ESKAPE Pathogens.
Not available
S-EPMC5444183 | biostudies-literature
UnknownResistome-based surveillance identifies ESKAPE pathogens as the predominant gram-negative organisms circulating in veterinary hospitals.
Not available
S-EPMC10513425 | biostudies-literature
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