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ProteomicsAn Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens
There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-...
ORGANISM(S): Escherichia Coli (ncbitaxon:562) 
2020-02-04 | MSV000084899 | MassIVE
ProteomicsAn Outer Membrane Protein-Targeting Antibiotic Against Resistant Gram-Negative Bacterial Pathogens
There is an urgent need for novel antibiotics against carbapenem and 3rd generation cephalosporin-resistant Gram-negative pathogens, for which the last-resort antibiotics have lost most of their efficacy. We describe here a novel class of synthetic antibiotics that was inspired from natural product-...
ORGANISM(S): Escherichia coli 
2019-10-22 | PXD010174 | Pride
Macrocyclic peptidomimetic antibiotics Novel molecular mode of action Lpt complex E.coli Dda Ompta (outer membrane-targeting antibiotics) Lc-ms/ms Bam complex Photoaffinity labeling Thermo q-exactive plus Interaction mapping Photo crosslinking Gram-negative eskape pathogens 
GenomicsEnterobacteriales and other Gram negative pathogens
Whole genome sequencing of other Enterobacteriales and Gram negative pathogens as part of MDU-PHL surveillance activities in Victoria, Australia Raw sequence reads
PRJNA870170 | ENA
GenomicsDevelopment and Characterization of Bacteriophage Cocktails targeting Gram-Negative ESKAPE Pathogens
Development and Characterization of Bacteriophage Cocktails targeting Gram-Negative ESKAPE Pathogens
PRJEB123093 | ENA
TranscriptomicsCirculating miRNA expression after subcutaneous injection of Gram negative and positive bacteria in the mice
To explore the circulating miRNA expression after subcutaneous injection of Gram negative and positive bacteria in the mice The recombinant specific Gram negative pathogens Escherichia coli (xen14) and Gram positive pathogens Staphyllococcus aureus (xen29) were purchased from the Caliper (Caliper, P...
ORGANISM(S): Mus musculus 
2014-01-01 | E-GEOD-49189 | biostudies-arrayexpress
GenomicsGram Negative Carbapenemase Detection Genome sequencing and assembly
Gram Negative Carbapenemase Detection Genome sequencing and assembly
PRJNA292904 | ENA
GenomicsGram-Negative Enterobacterales in Mali
Gram-Negative Enterobacterales from Paediatric Infections, Mali (2005-2023)"
PRJEB87282 | ENA
TranscriptomicsGene expression response to bacterial phagocytosis by S2 cells (control and eater RNAi knock down)
The Drosophila phagocytic receptor Eater is expressed specifically in phagocytic hemocytes. It contributes to host immune defense and is required for survival of bacterial infections. Eater is involved in recognition and phagocytosis of bacteria. We used microarrays to determine whether any gene exp...
ORGANISM(S): Drosophila melanogaster 
2011-08-24 | E-GEOD-31564 | biostudies-arrayexpress
GenomicsAlternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens
Alternative lipid synthesis in response to phosphate limitation promotes antibiotic tolerance in Gram-negative ESKAPE pathogens
PRJNA1154271 | ENA
UnknownThymine Sensitizes Gram-Negative Pathogens to Antibiotic Killing.
Not available
S-EPMC7875874 | biostudies-literature
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