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UnknownA small-molecule ARTS mimetic promotes apoptosis through degradation of both XIAP and Bcl-2.
Not available
S-EPMC7316745 | biostudies-literature
GenomicsNational Eye Institute Glaucoma Human Genetics Collaboration (NEIGHBOR) Consortium Glaucoma Genome-Wide Association Study

This is a case-control study of primary open angle glaucoma (POAG). POAG is an intraocular pressure (IOP) related progressive optic neuropathy that ultimately leads to blindness. For this study we have formed a collaborative consortium contributing 2170 POAG cases and 2347 controls with a unified...

phs000238.v1.p1 | EGA
UnknownSystematic Review and Meta-Analysis on the Prevalence of Radiotherapy-Induced Hypopituitarism in Adults With Primary Non-Pituitary Brain Tumours.
Not available
S-EPMC12046547 | biostudies-literature
UnknownComparing two advance care planning conversation activities to motivate advance directive completion in underserved communities across the USA: The Project Talk Trial study protocol for a cluster, randomized controlled trial.
Not available
S-EPMC9523194 | biostudies-literature
UnknownSystematic Review of Prevalence of Young Child Overweight and Obesity in the United States-Affiliated Pacific Region Compared With the 48 Contiguous States: The Children's Healthy Living Program.
Not available
S-EPMC4265894 | biostudies-literature
TranscriptomicsDifferential Expression of Chemokine and Matrix Re-Modelling Genes Explains Contrasting Schistosoma japonicum-induced Hepatopathology in Murine Models
The pathological outcomes of schistosomiasis are largely dependent on the molecular and cellular mechanisms of the host immune response. In this study, we demonstrate the variation of host gene expression which underlies the contrasting hepatic pathology observed between two inbred mouse strains fol...
ORGANISM(S): Mus musculus 
2010-11-30 | E-GEOD-25713 | biostudies-arrayexpress
TranscriptomicsCharacterising Host Gene Expression during the Recovery from Hepatic Schistosomiasis Japonica
In schistosomiasis japonica, the egg-induced granulomatous response and the development of extensive hepatic fibrosis is the main pathology. Information regarding the specific mechanisms associated with granuloma regression and the subsequent recovery events in the host liver are still limited. In t...
ORGANISM(S): Mus musculus 
2014-08-31 | E-GEOD-59276 | biostudies-arrayexpress
UnknownLongitudinal Proteomic Profiling of Cognition across an Aerobic Exercise Intervention.
Not available
S-EPMC12010053 | biostudies-literature
GenomicOncoArray: Prostate Cancer

Original description of the study: From ELLIPSE (linked to the PRACTICAL consortium), we contributed ~78,000 SNPs to the OncoArray. A large fraction of the content was derived from the GWAS meta-analyses in European ancestry populations (overall and aggressive disease; ~27K SNPs). We also ...

phs001391 | dbGaP
UnknownHigher dose corticosteroids in hospitalised COVID-19 patients requiring ventilatory support (RECOVERY): a randomised, controlled, open-label, platform trial.
Not available
S-EPMC11872607 | biostudies-literature
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