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UnknownLow-Dose Oral Cyclophosphamide and Methotrexate Maintenance for Hormone Receptor-Negative Early Breast Cancer: International Breast Cancer Study Group Trial 22-00.
Not available
S-EPMC5035120 | biostudies-literature
ProteomicsThe platelet releasate in healthy population and pregancy
Upon activation, platelets release a multitude of soluble and vesicular signals, collectively termed the ‘platelet releasate’ (PR). This PR plays an important role in haemostasis, wound healing and the inflammatory response. We and others have used qualitative/quantitative proteomic approaches to ch...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2018-08-29 | MSV000082866 | MassIVE
UnknownEpidemiology of skin changes in endangered Southern Resident killer whales (Orcinus orca).
Not available
S-EPMC10306181 | biostudies-literature
Transcriptomicsc-Src Modulates Estrogen-Induced Stress and Apoptosis in Estrogen-Deprived Breast Cancer Cells [MCF-7:5C]
The emergence of anti-estrogen resistance in breast cancer is an important clinical phenomenon affecting long-term survival in this disease. Identifying factors that convey cell survival in this setting may guide improvements in treatment. Estrogen (E2) can induce apoptosis in breast cancer cells th...
ORGANISM(S): Homo sapiens 
2014-07-18 | E-GEOD-59535 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human age-dichotomized ER+ breast tumors
To investigate the biological basis between aging and sporadic breast cancer incidence and prognosis, RNA samples from matched ER+ invasive breast cancers diagnosed in either young (â?¤45) or old (â?¥70) women were analyzed by expression microarrays Experiment Overall Design: ER+ breast cancers coll...
ORGANISM(S): Homo sapiens 
2008-06-16 | E-GEOD-8193 | biostudies-arrayexpress
TranscriptomicsMicroarray-based CGH in human cancer cell lines
This series represents the data set from the paper Assembly of microarrays for genome-wide measurement of DNA copy number appearing in Nat Genet 2001 Nov;29(3):263-4 and it's web supplement. Specimen procurement, labeling, hybridization and imaging protocols from Nat Genet 2001 Nov;29(3):263-...
ORGANISM(S): Homo sapiens 
2010-06-05 | E-GEOD-16 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human age-dichotomized ER+, N0 breast tumors reveals enhanced NF kappa B and AP-1 activity associated with antiestrogen resistant breast caner
Signaling pathways that converge on two different transcription factor complexes, NFκB and AP-1, have been identified in estrogen receptor (ER)-positive breast cancers resistant to the antiestrogen, tamoxifen. In this study, biomarkers co-ordinately up-regulated by NFKB and AP-1 with prognositic si...
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-7378 | biostudies-arrayexpress
TranscriptomicsPleiotropic actions of miR-153 support colorectal cancer progression by enhanced invasion and chemotherapy resistance
MiRNA expression profiling in 2 colorectal cancer cell lines derived from the same individual.
ORGANISM(S): Homo sapiens 
2012-02-02 | E-MEXP-3270 | biostudies-arrayexpress
GenomicsPD
WTCCC project samples from the Parkinson's disase cohort
EGAD00000000057 | EGA
GenomicsGenome wide association scan in Parkinson's disease
Genome-wide association scan was performed in 1,705 cases of parkinson's genotyped on the Illumina Human 660W SNP array, and 5,175 controls genotyped on the Illumina1.2M-Duo. Analysis was carried out on the overlaps set of SNPs.
EGAS00000000034 | EGA
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