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Naive human pluripotent stem cells (hPSCs) represent a pre-implantation epiblast state able to efficiently differentiate into embryonic and extraembryonic pre-implantation lineages and to self-organise into blastocyst-like structures called blastoids. Naive hPSCs maintenance commonly relies on mouse...
ORGANISM(S): Bos taurus (Bovine) Rattus norvegicus (Rat) 
2025-12-22 | PXD059820 | Pride
Naive pluripotent epiblast cells of the preimplantation murine embryo and their in vitro counterpart, embryonic stem (ES) cells, have the capacity to give rise to all cells of the adult. Such developmental plasticity is associated with global genome hypomethylation. It is unclear whether genome meth...
ORGANISM(S): Mus musculus (Mouse) 
2020-11-26 | PXD020385 | Pride
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