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TranscriptomicsMsi1 integrates APC loss and mTORC1 activation to promote intestinal stem cell transformation
Loss of the APC tumor suppressor in the intestinal epithelium initiates the majority of human colorectal adenocarcinomas. Constitutive β-catenin activation is thought to underlie tumorigenesis induced by loss of APC, however β-catenin activation alone does not recapitulate all APC-loss phenotypes,...
ORGANISM(S): Mus musculus 
2015-10-22 | E-GEOD-54598 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of rhesus macaques vaccinated with ALVAC-SIVgpe DNA + SIVgp120 protein subunit and unvaccinated controls after challenge with SIVmac251 - 3 wks post-infection
The SIVmac251 macaque model has been used to evaluate the efficacy of vaccine for HIV. Exposure of macaques to a single high dose of SIVmac251 results in transmission of multiple viral variants, which contrasts the few HIV variants typically transmitted in humans. In here, we investigated whether th...
ORGANISM(S): Macaca mulatta 
2013-03-01 | E-GEOD-37311 | biostudies-arrayexpress
TranscriptomicsGene expression profiling of rhesus macaques vaccinated with ALVAC-SIVgpe DNA + SIVgp120 protein subunit and unvaccinated controls after challenge with SIVmac251 - 11 wks post-infection
The SIVmac251 macaque model has been used to evaluate the efficacy of vaccine for HIV. Exposure of macaques to a single high dose of SIVmac251 results in transmission of multiple viral variants, which contrasts the few HIV variants typically transmitted in humans. In here, we investigated whether th...
ORGANISM(S): Macaca mulatta 
2013-03-01 | E-GEOD-37312 | biostudies-arrayexpress
UnknownGenome-wide association and transcriptome studies identify target genes and risk loci for breast cancer.
Not available
S-EPMC6465407 | biostudies-literature
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