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MetabolomicsEnergy-stress-mediated AMPK activation inhibits ferroptosis

Energy stress depletes ATP and induces cell death. Here we identify an unexpected inhibitory role of energy stress on ferroptosis, a form of regulated cell death induced by iron-dependent lipid peroxidation. We found that ferroptotic cell death and lipid peroxidation can be inhibited by treatment...

2023-01-31 | MTBLS1399 | MetaboLights
UnknownInhaled house dust mite induces pulmonary T helper 2 cytokine production.
Not available
S-EPMC3385347 | biostudies-literature
TranscriptomicsGene expression analysis of TIL rich HPV driven head and neck tumours reveals a distinct B-cell signature when compared to HPV independent tumours.
Purpose: Human papilloma virus (HPV) associated head and neck squamous cell carcinoma (HNSCC) has a better prognosis than HPV(-) negative cancer. This may be due, in part, to the higher number of tumour infiltrating lymphocytes (TIL) in HPV(+) tumours. We used RNAseq to evaluate whether these differ...
ORGANISM(S): Homo sapiens 
2016-09-01 | E-GEOD-72536 | biostudies-arrayexpress
UnknownSafety and survival with GVAX pancreas prime and Listeria Monocytogenes-expressing mesothelin (CRS-207) boost vaccines for metastatic pancreatic cancer.
Not available
S-EPMC4397277 | biostudies-literature
UnknownNeurocognitive function and CNS integrity in adult survivors of childhood hodgkin lymphoma.
Not available
S-EPMC3462045 | biostudies-literature
MetabolomicsChitin utilization by marine picocyanobacteria and the evolution of a planktonic lifestyle.
Marine picocyanobacteria Prochlorococcus and Synechococcus, the most abundant photosynthetic cells in the oceans, are generally thought to have a primarily single-celled and free-living lifestyle. However, while studying the ability of picocyanobacteria to supplement photosynthetic car...
2024-02-21 | MTBLS5229 | MetaboLights
UnknownCardiovascular Disease in Survivors of Childhood Cancer: Insights Into Epidemiology, Pathophysiology, and Prevention.
Not available
S-EPMC6804893 | biostudies-literature
TranscriptomicsThe impact of experience-dependent and independent factors on gene expression in songbird brain [e01]
Songbirds provide rich natural models for studying the relationships of brain anatomy, behavioral function, environmental signals and gene expression. Under the Songbird Neurogenomics Initiative, investigators from more than a dozen laboratories collected brain samples from six species of songbird ...
ORGANISM(S): Taeniopygia guttata 
2012-05-30 | E-GEOD-36705 | biostudies-arrayexpress
UnknownA protease for 'middle-down' proteomics.
Not available
S-EPMC3430368 | biostudies-literature
TranscriptomicsGene expression profiling data from sooty mangabeys treated with interferon alpha
In contrast to pathogenic HIV and SIV infection of humans and macaques, SIV infection of sooty mangabeys (SMs) is typically non-pathogenic despite high virus replication. A key feature of primary SIV infection of SMs is a strong type I interferon (IFN-I) response, characterized by massive up-regulat...
ORGANISM(S): Cercocebus atys 
2012-07-09 | E-GEOD-35460 | biostudies-arrayexpress
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