Griffin Justin J

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Unknown (3)
Metabolomics (3)

Repository

MetaboLights (3)

Technology Type

Mass spectrometry (3)

Instrument Platform

Thermo Q Exactive (Thermo Scientific) (1)
Orbitrap Fusion (Thermo Fisher Scientific)_negative (1)
Orbitrap Fusion (Thermo Fisher Scientific) (1)
Liquid Chromatography MS - Alternating (LC-MS (Alternating)) (1)

Publication Date

2020 (2)
2016 (1)

CHEBI ID

CHEBI:132051 (1)
CHEBI:83530 (1)
CHEBI:132050 (1)
CHEBI:157671 (1)
CHEBI:6541 (1)
CHEBI:83498 (1)
CHEBI:37941 (1)
CHEBI:2904 (1)
CHEBI:157672 (1)
CHEBI:132041 (1)
CHEBI:32635 (1)
CHEBI:9948 (1)
CHEBI:8776 (1)
CHEBI:8024 (1)
CHEBI:5959 (1)
CHEBI:4784 (1)
CHEBI:28593 (1)
CHEBI:4786 (1)
CHEBI:3127 (1)
CHEBI:6801 (1)

Metabolite Name

C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) related mtb – Sulphated and hydroxylated on C7H6N2O part (1)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) mtb (1)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) related mtb – sulphated (1)
C15H17N2O7S (C7H6N2O and C8H12O6S major two fragments) related mtb – glucuronidated (1)
C9H11NOS based mtb – coupled to C8H8N2O2 – sulphated (1)
C9H11NOS based mtb – coupled to C7H6N2O2 – sulphated (1)
C9H11NOS based mtb – coupled to C8H8N2O – glucuronidated (1)
C9H11NOS based mtb – coupled to C8H8N2O2 – glucuronidated – isomer II (1)
C9H11NOS based mtb – coupled to C8H8N2O2 – glucuronidated – isomer I (1)
C9H11NOS based mtb – coupled to C8H10N2 – glucuronidated (1)
C9H11NOS based mtb – coupled to C8H10N2 – sulphated (1)
Quinidine dihydroxylated Isomer II (1)
Quinidine dihydroxylated Isomer I (1)
Quinidine related mtb (1)
Quinidine reduced (+2H) trihydroxylated (1)
Quinidine oxidated (-2H) dihydroxylated Isomer II (1)
Quinidine oxidated (-2H) dihydroxylated Isomer I (1)
Quinidine reduced (+2H) dihydroxylated (1)
Quinidine hydroxylated (1)
Quinidine reduced (+2H) (1)
Paracetamol N-acetylcysteine and glutamine conjugate (1)
Paracetamol N-acetylcysteine conjugate sulfated (1)
Paracetamol cysteine-with-C4H9NO-adduct conjugate (1)
Paracetamol cysteine conjugate sulfated (1)
Paracetamol C3H4O3S conjugate (3-mercaptopuruvate?) (1)
Paracetamol C5H10N2O3S conjugate (L-cysteinylglycine?) (1)
Paracetamol C5H9NO4S conjugate (N-carboxymethylcysteine?) Isomer II (1)
Paracetamol C5H9NO4S conjugate (N-carboxymethylcysteine?) Isomer I (1)
Paracetamol cysteine conjugate glucuronide (1)
Paracetamol cysteine conjugate (1)

Release Date

2016 (1)
2012 (1)
2011 (1)

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Molecular networking coupled to high-resolution mass spectrometry fragmentation reveals a multitude of urinary antihypertensive drug metabolites

Mass spectrometry is the current technique of choice in studying drug metabolism. High-resolution mass spectrometry (HR-MS) in combination with fragment analysis (MS/MS) has the potential to contribute to rapid advances in this field. However, the data emerging from such fragmentation spectra pose c...

2016-05-23 | MTBLS307 | MetaboLights

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. congolense assay)

Livestock diseases caused by Trypanosoma congolense, T. vivax and T. brucei, collectively known as nagana, are responsible for billions of dollars in lost food production annually. There is an urgent need for novel therapeutics. Encouragingly, promising antitrypanosomal benzoxaboroles are under v...

2020-10-22 | MTBLS1309 | MetaboLights

Veterinary trypanocidal benzoxaboroles are peptidase-activated prodrugs (T. brucei assay)

2020-09-23 | MTBLS1474 | MetaboLights

Update on the third international stroke trial (IST-3) of thrombolysis for acute ischaemic stroke and baseline features of the 3035 patients recruited.

Not available

S-EPMC3286387 | biostudies-literature

The benefits and harms of intravenous thrombolysis with recombinant tissue plasminogen activator within 6 h of acute ischaemic stroke (the third international stroke trial [IST-3]): a randomised controlled trial.

Not available

S-EPMC3386495 | biostudies-literature

Effect of alteplase on the CT hyperdense artery sign and outcome after ischemic stroke.

Not available

S-EPMC4731690 | biostudies-literature