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TranscriptomicsKidney development time course
Array Design; Mouse Compugen 22K Spotted Oligo Author; Sean Grimmond Common Reference (Yes/No, ID); Yes Mouse universal Reference (Stratagene) Concentration; 100 Data processing/normalization; Lowess Normalisation GeneSpring) Developmental Stage; embryonic Diseased/Normal; normal Dye Swap; red/green...
ORGANISM(S): Mus musculus 
2010-06-09 | E-GEOD-2282 | biostudies-arrayexpress
TranscriptomicsKidney development time course
Array Design; Mouse Compugen 22K Spotted Oligo Author; Sean Grimmond Common Reference (Yes/No, ID); Yes Mouse universal Reference (Stratagene) Concentration; 100 Data processing/normalization; Lowess Normalisation GeneSpring) Developmental Stage; embryonic Diseased/Normal; normal Dye Swap; red/green...
ORGANISM(S): Homo sapiens Mus musculus 
2005-07-20 | GSE2282 | GEO
TranscriptomicsDeep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human Embryonic Stem cells
Cytoplasmic polyadenylated RNA from human embryonic stem cells (HES2) was separated on a 1.2% agarose and gel slices were excised corresponding to the following sizes: 0 to 0.5 kb; 0.5-2 kb; 2-3.5 kb; 3.5-6.5 kb and 6.5-20+ kb. Slices were dissolved and extracted RNA (1% of each fraction) was run on...
ORGANISM(S): Homo sapiens 
2010-10-20 | E-GEOD-24355 | biostudies-arrayexpress
TranscriptomicsDeep-transcriptome and ribonome sequencing redefines the molecular networks of pluripotency and the extracellular space in human Embryonic Stem cells (part 2)
Recent RNA-sequencing studies have shown remarkable complexity in the mammalian transcriptome. The ultimate impact of this complexity on the predicted proteomic output is less well defined. We have undertaken a strand-specific RNA sequencing of multiple cellular RNA fractions (>18Gb) to uncover the ...
ORGANISM(S): Homo sapiens 
2011-07-01 | E-GEOD-25842 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse naive and memory CD8+ T cells
This experiment compared the expression of mRNAs and noncoding RNAs between naive and memory CD8+ T cells, with the primary aim of identifying noncoding RNAs that were dynamically regulated during T cell differentiation.
ORGANISM(S): Mus musculus 
2008-11-01 | E-TABM-492 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of mouse resting and activated CD8+ T cells
This experiment compared the expression of mRNAs and noncoding RNAs between resting and activated CD8+ effector T cells, with the primary aim of identifying noncoding RNAs that were dynamically regulated during T cell activation.
ORGANISM(S): Mus musculus 
2008-11-01 | E-TABM-491 | biostudies-arrayexpress
GenomicsKidney development time course
Kidney development time course
PRJNA91337 | ENA
TranscriptomicsTP53 and TP63 modulation of Squamous PDAC
Based on the association of TP53 mutation and upregulated TP63 expression in the squamous subtype, we used cell lines derived from genetically engineered mouse models of PDAC (KRAS Trp53fl/+ and KRAS Trp53fl/+ Trp63fl/fl) to begin to unravel the functional consequences of these events in defining sq...
ORGANISM(S): Mus musculus 
2016-03-03 | E-MTAB-4415 | biostudies-arrayexpress
TranscriptomicsProtease activated receptor 2 (PAR2) on HEK293 activated by trypsin or 2f-LIGRLO-NH2
Human embryonic kidney cell (HEK293) were treated with PAR2 peptide agonist 2f-LIGRLO-NH2 (1.5h, 3h, 6h and 12h) or trypsin (6h). Comparison of genes similarly regulated by both treatments allowed better characterization of PAR2 induced response as both agonists had been reported as non-specific for...
ORGANISM(S): Homo sapiens 
2010-11-19 | E-GEOD-24332 | biostudies-arrayexpress
TranscriptomicsGenome-wide analysis of gene expression and intron retention during development in a U12-type splicing-deficient zebrafish mutant [RNA-seq]
To determine the global impact of the clbn mutation on gene expression and efficiency of U2- and U12-type splicing, we analyzed the transcriptome of 108hpf wt and clbn mutant larvae by microarrays and RNA sequencing. RNAseq data was used to characterize intron retention of U2-type and U12-type intro...
ORGANISM(S): Danio rerio 
2014-02-05 | E-GEOD-53758 | biostudies-arrayexpress
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