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TranscriptomicsBiological Similarities Exist between Oligoarticular and Polyarticular Subtypes of JIA Based on Age at Onset
Objective. To identify gene expression differences in peripheral blood from patients with early and late onset juvenile idiopathic arthritis (JIA). Methods. Peripheral blood mononuclear cells (PBMC) were isolated from 56 healthy controls and 104 patients with recent onset JIA (39 persistent oligo...
ORGANISM(S): Homo sapiens 
2011-02-14 | E-GEOD-20307 | biostudies-arrayexpress
TranscriptomicsExpression Signatures in Polyarticular JIA Show Heterogeneity and Offer a Molecular Classification of Disease Subsets
Objective. Microarray analysis was used to determine whether children with recent onset polyarticular juvenile idiopathic arthritis (JIA) exhibit biologically or clinically informative gene expression signatures in peripheral blood mononuclear cells (PBMC). Methods. Peripheral blood samples were o...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-GEOD-13849 | biostudies-arrayexpress
UnknownMonocyte MicroRNA Expression in Active Systemic Juvenile Idiopathic Arthritis Implicates MicroRNA-125a-5p in Polarized Monocyte Phenotypes.
Not available
S-EPMC5001902 | biostudies-literature
TranscriptomicsSubtype-specific peripheral blood gene expression profiles in recent onset JIA
Objective: A multi-center study of recent onset juvenile idiopathic arthritis (JIA) subjects prior to treatment with DMARDS or biologics was undertaken to identify peripheral blood gene expression differences between JIA subclasses and controls. Methods: PBMC from 59 healthy children and 136 JIA ...
ORGANISM(S): Homo sapiens 
2009-06-30 | E-GEOD-13501 | biostudies-arrayexpress
UnknownMacrophage activation syndrome in the era of biologic therapy.
Not available
S-EPMC5851441 | biostudies-literature
UnknownDistinct Gene Expression Signatures Characterize Strong Clinical Responders Versus Nonresponders to Canakinumab in Children With Systemic Juvenile Idiopathic Arthritis.
Not available
S-EPMC8238800 | biostudies-literature
UnknownBrief Report: Novel UNC13D Intronic Variant Disrupting an NF-κB Enhancer in a Patient With Recurrent Macrophage Activation Syndrome and Systemic Juvenile Idiopathic Arthritis.
Not available
S-EPMC5984660 | biostudies-literature
TranscriptomicsGene Expression Profiling in Peripheral Blood in Untreated New Onset Systemic Juvenile Idiopathic Arthritis
Systemic Juvenile Idiopathic Arthritis (sJIA) has been strongly associated with macrophage activation syndrome (MAS). To better understand the pathogenesid of sJIA and to facilitate the search for MAS biomarkers, we examine gene expression profiles in untreated new onset sJIA. 17 new onset sJIA pat...
ORGANISM(S): Homo sapiens 
2007-11-01 | E-GEOD-7753 | biostudies-arrayexpress
UnknownPathogenesis of systemic juvenile idiopathic arthritis: some answers, more questions.
Not available
S-EPMC4180659 | biostudies-literature
UnknownThe use of S100 proteins testing in juvenile idiopathic arthritis and autoinflammatory diseases in a pediatric clinical setting: a retrospective analysis.
Not available
S-EPMC6966841 | biostudies-literature
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