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TranscriptomicsChanges in gene expression resulting from expression of MN1 in human CD34+ cells
Reintroduction of CEBPA in MN1-overexpressing hematopoietic cells prevents their hyper-proliferation and restores myeloid differentiation. Forced expression of MN1 in primitive mouse hematopoietic cells causes acute myeloid leukemia and impairs all-trans retinoic acid (ATRA) induced granulocytic dif...
ORGANISM(S): Homo sapiens 
2010-10-26 | E-GEOD-16745 | biostudies-arrayexpress
TranscriptomicsGene expression profiles in mouse common myeloid progenitor (CMP) and leukemia cells expressing full-length MN1 or truncated versions of MN1 protein
We used Affymetrix microarrays to characterize gene expression profiles that were perturbed in common myeloid progenitor (CMP) cells due to enforced expression of full-length or truncated forms of MN1. Expression profiles of MN1-induced leukemias arising from whole bone marrow transduction were also...
ORGANISM(S): Mus musculus 
2013-06-13 | E-GEOD-38767 | biostudies-arrayexpress
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