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MetabolomicsGrowth-stage related diatom-bacteria interactions
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ORGANISM(S): Thalassiosira pseudonana 
ST001944 | MetabolomicsWorkbench
MetabolomicsOrganic Acids Modulate Systemic Metabolic Perturbation Caused by Salmonella Pullorum Challenge in Early-Stage Broilers
The objectives of this study were to determine the protective effects of organic acids (OA) in broilers exposed to Salmonella Pullorum challenge at early stage and to explore the potential benefits of OA by metabolomics analysis. The treatment groups included non-challenged, S. Pullorum-challenged, ...
2021-05-17 | MTBLS1274 | MetaboLights
MetabolomicsDynamic change of IDO1 activity predicts survival in patients with unresectable stage III NSCLC and chemoradiotherapy

OBJECTIVES: High activity of Indoleamine 2,3-dioxygenase1 (IDO1) in lung cancer patients converts tryptophan (Trp), which is the essential amino acid for T cell metabolism, to kynurenine (Kyn) and consequently suppresses anti-tumor immune responses. We aimed to track the dynamics...

2022-08-05 | MTBLS5267 | MetaboLights
MetabolomicsGrowth-Promoting Mechanisms of Synthetic Communities in Tomato and Wheat under Saline-Alkaline Stress
SynComs boosted saline-alkali resistance in tomato and wheat via host-specific reshaping of rhizosphere microhabitats and distinct core plant metabolic pathways.
2026-06-24 | MTBLS14847 | MetaboLights
MetabolomicsAssessment of phenotypic trait plasticity in the oilseed Camelina sativa using integrated early-stage abiotic stress and field studies

Connecting the characterisation of juvenile (pre-anthesis) plant stress responses undertaken in controlled environments to field agronomic performance is a challenge. The oilseed crop Camelina sativa (camelina), with its innate resilience and plasticity, presents an opportunity to understand both...

2026-02-09 | MTBLS9839 | MetaboLights
MetabolomicsTime-resolved decoding of metabolic signatures of in vitro growth of the hemibiotrophic pathogen Colletotrichum sublineolum
Metabolomics has emerged as a powerful approach to comprehensively interrogate cellular biochemistry. As such, we applied an untargeted liquid chromatography-mass spectrometry metabolomic strategy to elucidate metabolome changes in the anthracnose-causing hemibiotrophic sorghum pathogen, Colletotric...
2022-05-30 | MTBLS735 | MetaboLights
MetabolomicsCoupling Inflammatory Resolution to Osteogenesis: Lymphatic Vessels as Stage-specific Niche Regulators in Skeletal Healing

Skeletal healing requires the coordinated resolution of inflammation and precise lineage commitment of mesenchymal progenitors, yet the mechanisms coupling these processes remain incompletely defined. Here, we reveal that lymphatic vessels in bone serve as dynamic orchestrato...

2026-01-17 | MTBLS13645 | MetaboLights
MetabolomicsDynamic Characteristics of Primary and Secondary Polar Metabolites in Cabernet Sauvignon Grapes at Different Growth Stages in the Ningxia Wine Region

This study focuses on the Helan Mountain East Foothills region of Ningxia, a typical continental climate wine-growing area, with Cabernet Sauvignon grapes as the subject. It combines trime-thylsilyl derivatization -Gas Chromatography-Mass Spectrometry (TMS-GC-MS) technology and the independently ...

2026-01-22 | MTBLS13742 | MetaboLights
MetabolomicsRhizophagus intraradices improves soybean microbiome niche under saline-alkaline stress across critical growth stages

Background

Soil salinization and alkalization severely threaten soybean growth and yield. Arbuscular mycorrhizal fungi (AMF), specifically Rhizophagus intraradices (Ri), enhance stress tolerance and soil quality, yet their mechanisms in regulating microbial-metabolite interactions during cr...

2026-01-12 | MTBLS13661 | MetaboLights
MetabolomicsHost autophagy mediates organ wasting and nutrient mobilization for tumor growth
During tumor growth-when nutrient and anabolic demands are high-autophagy supports tumor metabolism and growth through lysosomal organelle turnover and nutrient recycling. Ras-driven tumors additionally invoke non-autonomous autophagy in the microenvironment to support tumor growth, in part through ...
2021-09-24 | MTBLS2771 | MetaboLights
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