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MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation, targeted lipid mediator profiling

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1381 | MetaboLights
MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation - DIA lipid mediator validation

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1382 | MetaboLights
MetabolomicsLipidCreator workbench to probe the lipidomic landscape - Platelet isolation and stimulation, Targeted Phospho and Glycerolipid Profiling

Here we present LipidCreator, a software that fully supports targeted lipidomics assay development. LipidCreator offers a comprehensive framework to compute MS/MS fragment masses for over 60 lipid classes. LipidCreator provides all functionalities needed to define fragments, manage stable isotope...

2020-04-15 | MTBLS1369 | MetaboLights
TranscriptomicsMouse Soleus Muscle Chronic Electrical Stimulation Study
Stimulation of the mouse hindlimb via the sciatic nerve was used to induce contractions for 4 hours to investigate acute muscle gene activation in a model of muscle phenotype conversion. Initial force production (1.6 + 0.1 g/g body weight) declined 45% within 10 min and was maintained for the remain...
ORGANISM(S): Mus musculus 
2010-06-01 | E-GEOD-14391 | biostudies-arrayexpress
TranscriptomicsModulation of brain dead induced inflammation by vagus nerve stimulation
Because the vagus nerve is implicated in control of inflammation, we investigated if brain death causes impairment of the parasympathetic nervous system, hence contributing to inflammation. Brain death (BD) was induced in rats. Anaesthetised ventilated rats (NBD) served as control. Heart rate varia...
ORGANISM(S): Rattus norvegicus 
2010-05-19 | E-GEOD-16483 | biostudies-arrayexpress
MetabolomicsOptimised LC-MS Metabolomic Profiling Reveals Emergent Changes to Monocyte Metabolism in Response to Lipopolysaccharide
Immunometabolism examines the links between immune cell function and metabolism. Dysregulation of immune cell metabolism is now an established feature of innate immune cell activation. Advances in liquid chromatography mass spectrometry (LC-MS) technologies have allowed discovery of unique insights ...
2025-11-17 | MTBLS6730 | MetaboLights
TranscriptomicsExpression data from advanced Parkinson's disease (PD) patients leukocytes - prior to and following deep brain stimulation (DBS) treatment in on and off stimulation conditions, and matched healthy control (HC) subjects
Sub-thalamic deep brain stimulation (DBS) reversibly modulates ParkinsonM-bM-^@M-^Ys disease (PD) motor symptoms, providing an unusual opportunity to compare leukocyte transcripts in the same subjects before and after neurosurgery and after disconnecting the stimulus (ON-and OFF-stimulus). Here, we ...
ORGANISM(S): Homo sapiens 
2012-01-09 | E-GEOD-23676 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human HeLa cells and MCF10A cells subject to EGF stimulation
This SuperSeries is composed of the following subset Series:; GSE6783: Expression data from HELA cells subject to EGF stimulation; GSE6784: Expression data from MCF10A cells subject to EGF stimulation Experiment Overall Design: Refer to individual Series
ORGANISM(S): Homo sapiens 
2008-06-15 | E-GEOD-6786 | biostudies-arrayexpress
Proteomicsfetal growth restriction_pancreas_differences in nutritional condition
Quantification of proteins in the pancreas of fetal growth restriction.
ORGANISM(S): Rattus Rattus (black Rat) 
2022-06-07 | PXD026502 | JPOST Repository
ProteomicsEarly Signaling Dynamics of EGFR
Despite extensive study of the epidermal growth factor receptor (EGFR) signaling network, the immediate post-translational changes that occur in response to growth factor stimulation remain poorly characterized; as a result, the biological mechanisms underlying signaling initiation remain obscured. ...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2017-03-29 | MSV000080800 | MassIVE
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