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TranscriptomicsMetastatic Cascade is Reflected in the Gene Expression of Metastatic Canine Mammary Carcinomas Similar to Human Breast Cancer
Proliferation, dedifferentiation, loss of cell-cell contacts and angiogenesis are among the first steps of the metastasis cascade. The complex molecular pathways associated with these events in canine mammary tumors are mostly unknown and the value of this spontaneous canine tumor as a comparative m...
ORGANISM(S): Canis lupus familiaris 
2010-12-01 | E-GEOD-22516 | biostudies-arrayexpress
TranscriptomicsMetastatic Canine Mammary Carcinomas
[original title] Metastatic Canine Mammary Carcinomas can be Identified by a Gene Expression Profile that partly Overlaps with Human Breast Cancer Profiles. Introduction: Similar to human breast cancer mammary tumors of the female dog are commonly associated with a fatal outcome due to the develop...
ORGANISM(S): Canis lupus familiaris 
2010-12-01 | E-GEOD-20718 | biostudies-arrayexpress
TranscriptomicsCanine Cutaneous Peripheral Nerve Sheath Tumours versus Fibrosarcomas can be Differentiated by Neuroectodermal Marker Genes in their Transcriptome.
The diagnostic differentiation of canine fibrosarcomas and peripheral nerve sheath tumors (PNST) is mainly based on their histopathologic phenotype. Histologic differentiation of these tumors can, however, be difficult and there is a lack of immunohistochemical markers to prove their histogenic orig...
ORGANISM(S): Canis lupus familiaris 
2012-10-30 | E-GEOD-34382 | biostudies-arrayexpress
TranscriptomicsIdentification of Six Potential Markers for the Detection of Circulating Canine Mammary Tumor Cells in the Peripheral Blood
Circulating tumor cells in the peripheral have proven to be independent prognostic factors for overall survival the monitoring of therapeutic success of human breast cancer patients. Postmortem morphologic evidence also points towards the presence of circulating tumor cells in the peripheral blood o...
ORGANISM(S): Canis lupus familiaris 
2011-12-10 | E-GEOD-25586 | biostudies-arrayexpress
TranscriptomicsRNAseq of Calu-3 epithelial cells treated with Cyclosporin A
Calu-3 cells are human lung cancer cells that serve as a model of respiratory epithelial cell model. Here, Calu-3 cells are used as a cell system for Middle East respiratory syndrome coronavirus and treated with Cyclosporin A To assess the effect of Cyclosporin A on the host cells, uninfected cells ...
ORGANISM(S): Homo sapiens 
2020-08-01 | E-MTAB-8222 | biostudies-arrayexpress
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