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TranscriptomicsAlu element-containing RNAs maintain nucleolar structure and function
We have isolated, analyzed and compared the RNA content of various cell compartments including total RNA, nucleolplasmic RNA and nucleolar RNA. In addition, cells have been subjected to various treatment to specifically inhibit each of the RNA polymerases I, II and III, as well as protein synthesis...
ORGANISM(S): Homo sapiens 
2015-10-16 | E-MTAB-3460 | biostudies-arrayexpress
TranscriptomicsSIRT7-dependent deacetylation of the U3-55k protein controls pre-rRNA processing [CLIP-Seq]
SIRT7 is an NAD+-dependent protein deacetylase with important roles in ribosome biogenesis and cell proliferation. Previous studies have established that SIRT7 is associated with RNA polymerase I, interacts with pre-rRNA and promotes rRNA synthesis. Here we show that SIRT7 is also associated with sn...
ORGANISM(S): Homo sapiens 
2016-01-07 | E-GEOD-76578 | biostudies-arrayexpress
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