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MetabolomicsUntargeted metabolomics analysis of BO, GSC and GSC-BO (CO) groups
Patient-derived GBM stem-like cells (GSCs) were first cultured to form glioma spheroids and then co-cultured with the brain organoid (BO) derived from fetal rat brains for 72 hours. To investigate the metabolite produced by GBM under physiological conditions, , we used an in vitro co-culture model f...
2026-04-15 | MTBLS14187 | MetaboLights
TranscriptomicsExpression data for minimally invasive glioblastoma stem-like cell (GSC) plasma membrane markers
We compared whole genome expression profiles of GSCs with normal human cortex, human neural stem cells (hNSC) from fetal cortex, glioblastoma (GBM) primary, and recurrent tumors to find GSC-specific plasma membrane transcripts. All of the expression profiles were batch normalized by a robust multich...
ORGANISM(S): Homo sapiens 
2013-11-14 | E-GEOD-51822 | biostudies-arrayexpress
TranscriptomicsExpression data from glioblastoma stem cell clones (GSC)
Comparison of treatment sensitive GSC clones (TSGC) with treatment resistant GSC clones (TRGC). We used microarrays to identify molecular signatures of TRGC (upregulated genes). We used radiation treatment (RT) or RT plus TMZ to select treatment resistant GSC clones (TRGC)
ORGANISM(S): Homo sapiens 
2013-11-01 | E-GEOD-46531 | biostudies-arrayexpress
GenomicsClostridium beijerinckii strain:GSC BB1
Clostridium beijerinckii strain:GSC BB1 Genome sequencing and assembly
PRJNA565649 | ENA
Transcriptomicshuman glioma stem cells (GSC) : undifferentiated versus differentiated in presence or absence of active GSK3beta
Transcriptional profilling of human GSC comparing undifferentiated (ND) and differentiated (Diff 0.5%) GSC treated or not with TWS119 (LW) an inhibitor of GSK3beta Glioblastomas (GBM) are the most common form of primary brain tumors. Highly vascularized, infiltrating, resistant to current therapies,...
ORGANISM(S): Homo sapiens 
2016-03-23 | E-GEOD-79478 | biostudies-arrayexpress
GenomicsRNA sequencing facilitates quantitative analysis of NPC cells, NPC-KRASG13D, and GSC cells (including U251-GSC, U118MG-GSC) transcriptomes
RNA sequencing facilitates quantitative analysis of NPC cells, NPC-KRASG13D, and GSC cells (including U251-GSC, U118MG-GSC) transcriptomes
PRJNA952123 | ENA
TranscriptomicsGenome-wide CRISPR-Cas9 screens reveal loss of redundancy between PKMYT1 and WEE1 in Glioblastoma stem-like cells
To identify new therapeutic targets for Glioblastoma (GBM), we performed genome-wide CRISPR-Cas9 "knockout" (KO) screens in patient-derived GBM stem-like cells (GSCs) and human neural stem/progenitors (NSCs), non-neoplastic stem cell controls, for genes required for their in vitro growth. ...
ORGANISM(S): Homo sapiens 
2016-02-15 | E-GEOD-70038 | biostudies-arrayexpress
TranscriptomicsGene expression in glioblastoma (GBM) tissues, glioblastoma stem-like cell (GSC) cultures and neural foetal cell line (NFC)
This microarray contains expression data for two GBM tissue samples, four GSC cultures grown as spheres and one NFC culture grown as spheres Total RNA was isolated from GSC cultures and GBM tissues
ORGANISM(S): Homo sapiens 
2015-11-26 | E-GEOD-60705 | biostudies-arrayexpress
TranscriptomicsTaqMan Low Density Arrays on Glioma Stem-like Cell lines (GSC-1 to 11)
Determination of pluripotency and differentiation-related genes expression in GSC-1 to 11 11 GSCs lines and human ES (H1) cell line as reference
ORGANISM(S): Homo sapiens 
2012-02-15 | E-GEOD-35811 | biostudies-arrayexpress
Genomics3D-GSC expression profiles
In this study, we used RNA-sequencing gene expression profiling in order to characterize specific phenotypic traits in DIPG-derived glioma stem cell (GSC) models. Twenty-two primary GSC models derived from biopsies collected at diagnosis were cultured in an ECM-mimicking compound before for RNA extr...
EGAS00001007182 | EGA
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