Little is known about metabolic vulnerabilities in oncogene-driven lung cancer. Here, we performed a phosphoproteomic screen in anaplastic lymphoma kinase (ALK)-rearranged (“ALK+”) patient-derived cell lines and identified guanylate kinase 1 (GUK1), a GDP-synthesizing enzyme, as a novel target of AL...
ORGANISM(S): Homo sapiens (Human)
