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TranscriptomicsTranscription profiling of human mesenchymal stromal cells to reveal senescence associated gene expression changes
Transcription profiling of human mesenchymal cells (MSCs) after ex vivo expansion under culture conditions supporting extensive cell proliferation. Highly efficient cell expansion within short time (~40 days) and comparison of gene expression profiles from MSCs after primary seeding, defined as earl...
ORGANISM(S): Homo sapiens 
2009-12-31 | E-MEXP-1997 | biostudies-arrayexpress
TranscriptomicsComparison of the expression profiles of wild type (WT) and Oct-6-deficient (Oct-6-/-) macrophages in response to poly(I:C) treatment
Identification of target genes of the POU-transcription factor Oct-6 in macrophages after poly(I:C) treatment WT and Oct-6-/- fetal-liver macrophages were treated with poly(I:C) for 8 hours or were left untreated (3 independent expreiments = biological replicates). 200 genes differentially regulated...
ORGANISM(S): Mus musculus 
2010-08-01 | E-GEOD-22691 | biostudies-arrayexpress
no omics definedTranscription profiling of mononucleated cells cultured in EndoCult and reference media
Impact of the culture system on functional differentiation of Mononucleated cells
ORGANISM(S): Homo sapiens 
2006-12-01 | E-MEXP-723 | biostudies-arrayexpress
TranscriptomicsGene expression in hypoxic non-small cell lung cancer
Hypoxia triggers aggressive cancer growth and contributes to chemotherapy resistance. Novel therapeutic strategies aim at targeting hypoxia activated signaling pathways. Tumor hypoxia not only affects neoplastic tumor cells but also the surrounding stroma cells. Therefore, a novel ex vivo model was ...
ORGANISM(S): Homo sapiens 
2011-07-27 | E-GEOD-30979 | biostudies-arrayexpress
TranscriptomicsRNA expression analysis in a multigeneration feeding study of OF1 outbred mice
To analyze the effect of different aliments, male OF1 mice were fed ad libitum with a custom-made diet containing 33% maize derived from three cultivars containing comparable nutritional values for multiple generations. To evaluate possible effects on the gene expression in the small intestine, the...
ORGANISM(S): Mus musculus 
2013-02-20 | E-GEOD-44396 | biostudies-arrayexpress
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