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Proteomicscomparative phosphoproteomics uncover proteins from the mechanobiome in Entamoeba histolytica
Entamoeba histolytica is a protozoan parasite and the causative agent of amoebiasis in humans. This amoeba invades human tissues by taking advantage of the actin-rich cytoskeleton to move, enter the tissue matrix, kill and phagocyte human cells. During events leading to tissue invasion, E. histolyti...
ORGANISM(S): Entamoeba histolytica Entamoeba histolytica 
2023-05-15 | PXD040787 | Pride
Entamoeba Wortmannin Phosphoproteomics 
ProteomicsNew insights into amebiasis using a human 3D-intestinal model
Entamoeba histolytica, the agent of amebiasis, colonizes the human colon and can invade the lining of the colon to disseminate in the deep layers of the intestine. Amebiasis mainly affects poor people in developing countries, where the barriers between human feces and food or water are inadequate. H...
ORGANISM(S): Homo sapiens (Human) Entamoeba histolytica HM-1:IMSS 
2020-03-24 | PXD015312 | Pride
Mass spectrometry Infection 3d-intestinal model 
ProteomicsCellular and proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica
This work represents the in-depth proteomics analysis of subcellular compartments in E.histolytica and allows a detailed map of vesicle traffic components in an ancient single-cell ogranism that lacks a stereotypical ER and Golgi apparatus
ORGANISM(S): Entamoeba histolytica HM-1:IMSS 
2014-08-13 | PXD000770 | Pride
Endomembrance vesicles proteomics 
UnknownStructural genomics applied to the rust fungus Melampsora larici-populina reveals two candidate effector proteins adopting cystine knot and NTF2-like protein folds.
Not available
S-EPMC6889267 | biostudies-literature
TranscriptomicsExtensive transcriptome analysis identifies essential genes sustaining intestinal invasion by Entamoeba histolytica
The main goal of this study was to analyse gene expression change of virulent amoebic strain (i.e. HM1:IMSS) in different environmental contexts, including isolation from animal liver, contact with the human colon and short prolonged in vitro culture.
ORGANISM(S): Entamoeba histolytica 
2016-09-30 | E-MTAB-4882 | biostudies-arrayexpress
Proteomicssecretome study for human hepatic model during entamoeba invasion
Investigations of human parasitic diseases depend on the availability of appropriate in vivo animal models and ex vivo experimental systems, and are particularly difficult for pathogens whose exclusive natural hosts are humans, as for Entamoeba histolytica, the protozoan parasite responsible for amo...
ORGANISM(S): Bos taurus (Bovine) Homo sapiens (Human) Entamoeba histolytica HM-1:IMSS-A 
2014-08-13 | PXD000893 | Pride
Entamoeba Lsec cell Proteomics Secretome Hepatic cell 
TranscriptomicsExpression of virulent and non-virulent E.histolytica in contact with the human colon
Evaluation of transcript levels of two strains E.Histolytica (virulent and avirulent) in two conditions (in culture or in contact with a human colon explant)
ORGANISM(S): Entamoeba histolytica 
2012-08-01 | E-MTAB-1201 | biostudies-arrayexpress
TranscriptomicsTranscriptional Metronidazole treatment
This study aims to search for the effect of 50uM Metronidazole against Entamoeba histolytica and thereby elucidating their mechanism of action
ORGANISM(S): Entamoeba histolytica 
2014-01-14 | E-MTAB-1763 | biostudies-arrayexpress
UnknownImpact of Number of Passes Before Rescue Therapy in Thrombectomy for Basilar Artery Strokes.
Not available
S-EPMC12778766 | biostudies-literature
UnknownPenumbral Rescue by normobaric O = O administration in patients with ischemic stroke and target mismatch proFile (PROOF): Study protocol of a phase IIb trial.
Not available
S-EPMC10759237 | biostudies-literature
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