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ProteomicsMicrobial metabolite Indole-3-propionic acid drives mitochondrial respiration in CD4+ T cells to confer protection against intestinal inflammation
The gut microbiota and its metabolites critically regulate immune cell phenotype, function, and energy metabolism. We screened a collection of gut microbiota-related metabolites to identify modulators of mitochondrial metabolism in T cells. Here, we show that indole-3-propionic acid (IPA) stimulates...
ORGANISM(S): Mus musculus (Mouse) 
2025-08-28 | PXD057537 | Pride
Gut microbiota Indole-3-propionic acid (ipa) Immunometabolism Inflammatory bowel disease (ibd) Cd4+ t cell 
UnknownLow-Temperature Aqueous Alteration of Chondrites.
Not available
S-EPMC11794400 | biostudies-literature
TranscriptomicsGene expression analysis of human pediatric mesenchymal stem cells (hpMSCs) upon expression of EWS-FLI-1
Cancer stem cells (CSCs) display plasticity and self-renewal properties reminiscent of normal tissue stem cells, but the events responsible for their emergence remain obscure. We recently identified CSCs in Ewing sarcoma family tumors (ESFTs) and showed that they retain mesenchymal stem cell (MSC) p...
ORGANISM(S): Homo sapiens 
2011-08-04 | E-GEOD-31215 | biostudies-arrayexpress
UnknownBi-allelic variants in INTS11 are associated with a complex neurological disorder.
Not available
S-EPMC10183469 | biostudies-literature
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