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Single mutation in the flavivirus envelope protein hinge region increases neurovirulence for mice and monkeys but decreases viscerotropism for monkeys: relevance to development and safety testing of live, attenuated vaccines.
Not available
S-EPMC135909
|
biostudies-literature
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A single amino acid substitution in the envelope protein of chimeric yellow fever-dengue 1 vaccine virus reduces neurovirulence for suckling mice and viremia/viscerotropism for monkeys.
Not available
S-EPMC514991
|
biostudies-literature
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Construction, safety, and immunogenicity in nonhuman primates of a chimeric yellow fever-dengue virus tetravalent vaccine.
Not available
S-EPMC114964
|
biostudies-literature
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Sequential immunization with heterologous chimeric flaviviruses induces broad-spectrum cross-reactive CD8+ T cell responses.
Not available
S-EPMC2903744
|
biostudies-literature
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Modified vaccinia Ankara vaccine expressing Marburg virus-like particles protects guinea pigs from lethal Marburg virus infection.
Not available
S-EPMC7468113
|
biostudies-literature
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Recombinant chimeric yellow fever-dengue type 2 virus is immunogenic and protective in nonhuman primates.
Not available
S-EPMC112032
|
biostudies-literature
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A single immunization with a modified vaccinia Ankara vectored vaccine producing Sudan virus-like particles protects from lethal infection.
Not available
S-EPMC9314403
|
biostudies-literature
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A Zika Vaccine Targeting NS1 Protein Protects Immunocompetent Adult Mice in a Lethal Challenge Model.
Not available
S-EPMC5677088
|
biostudies-literature
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A Single Dose of Modified Vaccinia Ankara Expressing Lassa Virus-like Particles Protects Mice from Lethal Intra-cerebral Virus Challenge.
Not available
S-EPMC6789566
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biostudies-literature
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A Single Dose of Modified Vaccinia Ankara expressing Ebola Virus Like Particles Protects Nonhuman Primates from Lethal Ebola Virus Challenge.
Not available
S-EPMC5770434
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biostudies-literature
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