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TranscriptomicsDNA methylation analysis of the U937 cell line
DNA methylation profiling of gene promoters in the human myeloid cell line U937. Bisulphite converted DNA from wildtype U937 cells was hybridised to the Illumina Infinium HumanMethylation27 BeadChip to determine the methylation pattern of the U937 cell line.
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-60734 | biostudies-arrayexpress
TranscriptomicsGene expression changes upon knockdown of DEK in the U937 cell line
Gene expression profiling of U937 cells upon knockdown of the DEK oncogene by two different shRNAs (shDEK14 and shDEK17). The DEK oncogene was knocked down by shRNA to study the changes in gene expression.
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-60732 | biostudies-arrayexpress
GenomicsGenome-wide mapping of DEK binding in the U937 cell line
We find that the DEK oncoprotein preferentially binds close to the transcription start sites of highly and ubiquitously expressed genes. Sequencing of DNA precipitated by an antibofy against the DEK oncoprotein (ChIP-seq).
ORGANISM(S): Homo sapiens 
2014-09-26 | E-GEOD-60692 | biostudies-arrayexpress
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