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TranscriptomicsExpression data from pregnant rat hearts
Hyperhomocysteinemia (HHcy) causes cardiovascular dysfunction and is associated with many complications during pregnancy related to reduced NO bioactivity. The mechanisms of HHcy on the NO-dependent control of myocardial metabolism was compared with L-NAME, which directly inhibits NO bioavailability...
ORGANISM(S): Rattus norvegicus 
2015-06-12 | E-GEOD-30308 | biostudies-arrayexpress
TranscriptomicsGenes induced after BDV infection in Sprague Dawley and Lewis rats
Borna Disease Virus (BDV) is a neurotropic virus that persistently infects neurons in the central nervous system of various hosts, including rats. Although BDV is known to be an IFN sensitive virus, determination of the cellular mRNA transcript levels revealed the induction of IFN-stimulated genes i...
ORGANISM(S): Rattus norvegicus 
2013-06-26 | E-GEOD-41540 | biostudies-arrayexpress
TranscriptomicsRole of ICOS:ICOSL interaction in acute GVHD
Inducible co-stimulator (ICOS) interaction with its ligand (ICOSL) is involved in several T cell effector functions. While blockade of ICOS:ICOSL interaction in chronic graft versus host disease (GVHD) seems benefi cial, results for acute GVHD remain controversial. To further elucidate its role in a...
ORGANISM(S): Mus musculus 
2009-09-14 | E-GEOD-17995 | biostudies-arrayexpress
MetabolomicsTissue, urine and serum NMR metabolomics dataset from a 5/6 nephrectomy rat model of chronic kidney disease

Serum, urine and tissue from a rat model of chronic kidney disease (CKD) were analysed using nuclear magnetic resonance (NMR) spectroscopy-based metabolomics methods, and compared with samples from sham operated rats. Both urine and serum were sampled at multiple timepoints, and the results have ...

2020-11-16 | MTBLS2052 | MetaboLights
TranscriptomicsTranscriptome analysis of MENXM-bM-^@M-^Qassociated rat pituitary adenomas identifies novel molecular mechanisms involved in the pathogenesis of human pituitary gonadotroph adenomas
Gonadotroph adenomas comprise 15M-bM-^@M-^S40 % of all pituitary tumors, are usually non-functioning and are often large and invasive at presentation. Surgery is the first-choice treatment, but complete resection is not always achieved, leading to high recurrence rates. As gonadotroph adenomas poorl...
ORGANISM(S): Rattus norvegicus 
2013-07-10 | E-GEOD-23207 | biostudies-arrayexpress
TranscriptomicsExpression data from female rat kidney: pathophysiology of proteinuria
This study was designed to investigate gene expression in kidneys of adult female Sabra rats (SBH/y and SBN/y rat strains) with two indwelling kidneys or after uni-ninephrectomy, seeking those genes that are differentially expressed between the two strains, and between animals with one or two kidney...
ORGANISM(S): Rattus norvegicus 
2009-01-31 | E-GEOD-14666 | biostudies-arrayexpress
GenomicsGenome-wide DNA methylation profiling reveals epigenetic changes in the rat nucleus accumbens associated with cross-generational effects of adolescent THC exposure
Drug exposure during critical periods of development is known to have lasting effects, increasing one’s risk for developing mental health disorders. Emerging evidence has also indicated the possibility for drug exposure to even impact subsequent generations. Our previous work demonstrated that adole...
ORGANISM(S): Rattus norvegicus 
2015-06-19 | E-GEOD-69984 | biostudies-arrayexpress
UnknownA Novel Approach to Developing Disease and Outcome-Specific Social Risk Indices.
Not available
S-EPMC10156642 | biostudies-literature
TranscriptomicsGamma delta T cells isolated from spleen of cold-exposed rats against room-temperature placed control
Wistar male rats were exposed of cold for one day or 14 days. Control group was placed into room temperature. Gamma delta T cells were FACS sorted from spleen.
ORGANISM(S): Rattus norvegicus 
2023-10-30 | E-MTAB-13420 | biostudies-arrayexpress
MetabolomicsAutomated, Parallel Mass Spectrometry Imaging and Structural Identification of Lipids
We report a method that enables automated data-dependent acquisition of lipid tandem mass spectrometry data in parallel with a high-resolution mass spectrometry imaging experiment. The method does not increase the total image acquisition time and is combined with automatic structural assignment. Thi...
2018-05-21 | MTBLS597 | MetaboLights
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