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MetabolomicsExogenous L-Alanine promotes phagocytosis multidrug-resistant bacterial pathogens (L-Alanine-treated macrophage metabolomics)

Multidrug-resistant bacteria present a major threat to public health. Therefore, new drugs or approaches are urgently needed to manage and mitigate this threat. Here, we screen the molecular candidates that allow the survival of mice upon Vibrio parahaemolyticus infection by integrated p...

2024-09-26 | MTBLS7986 | MetaboLights
TranscriptomicsGene expression data of Lsd1fl/fl and Lsd1fl/fl Mx1Cre CD150+ CD48- lin- c-Kit+ Sca-1+ LT-HSCs
We discovered that mice that lack Lsd1 in hematopoietic cells were exhibited increased frequencies of CD150+ CD48- lin- c-Kit+ Sca-1+ LT-HSCs, but completely lacked the lin- c-Kit+ Sca-1- myeloid progenitor compartment. To determine the genes altered by Lsd1-loss, CD150+ CD48- lin- c-Kit+ Sca-1+ LT-...
ORGANISM(S): Mus musculus 
2013-06-25 | E-GEOD-40284 | biostudies-arrayexpress
UnknownAnatomical, Physiological, and Transcriptome Analyses Revealing Pod Shattering of <i>Medicago ruthenica</i> Associated with Pericarp Lignin Biosynthesis.
Not available
S-EPMC12467310 | biostudies-literature
UnknownPore-Forming Protein LIN-24 Enhances Starvation Resilience in Caenorhabditis elegans by Modulating Lipid Metabolism and Mitochondrial Dynamics.
Not available
S-EPMC11860826 | biostudies-literature
UnknownPhysiological Mechanisms and Core Genes in Response to Saline-Alkali Stress in Foxtail Millet (<i>Setaria italica</i> L.).
Not available
S-EPMC12190892 | biostudies-literature
TranscriptomicsThe RNA Pol II Elongation Factor Ell3 Marks Enhancers in ES Cells and Primes Future Gene Activation
Enhancers play a central role in precisely regulating the spatiotemporal expression of developmentally regulated genes. The molecular mechanisms and factors required for controlling the inactive or poised enhancers and their function in future gene activation remain elusive. Here, we have identified...
ORGANISM(S): Mus musculus 
2012-12-30 | E-GEOD-38148 | biostudies-arrayexpress
TranscriptomicsmicroRNA expression in murine hematopoietic stem cells
MicroRNAs influence hematopoietic differentiation, but little is known about their effects on the stem cell state. Here, we report that the microRNA processing enzyme Dicer is essential for stem cell persistence in vivo and a specific microRNA, miR-125a controls the size of the stem cell population ...
ORGANISM(S): Mus musculus 
2010-08-14 | E-GEOD-22450 | biostudies-arrayexpress
UnknownCNP signal pathway up-regulated in rectum of depressed rats and the interventional effect of Xiaoyaosan.
Not available
S-EPMC4316094 | biostudies-literature
TranscriptomicsThe regulation of miRNA expression by DNA methylation in hepatocellular carcinoma
Emerging evidences indicate that microRNAs (miRNAs) are often deregulated and have fundamental roles in hepatocellular carcinoma (HCC). However, the mechanism underlying miRNA dysregulation in HCC is still elusive. In this report, we used an integrated analysis strategy combining methylated DNA immu...
ORGANISM(S): Homo sapiens 
2015-08-05 | E-GEOD-49554 | biostudies-arrayexpress
MetabolomicsComparative metabolomics reveals serum metabolites changes in goats during different developmental stages

Goats can provide meat, milk and skins for humans and are livestock with high economic benefits. However, despite their economic significance, the comprehensive analysis of goats' serum metabolic profile and its intricate alterations throughout their developmental journey remains conspicuously ab...

2024-06-04 | MTBLS8944 | MetaboLights
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