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MetabolomicsAcupuncture Synergized With Bortezomib Improves Survival of Multiple Myeloma Mice via Decreasing Metabolic Ornithine
Multiple myeloma (MM) is a hematological malignancy worldwide in urgent need for novel therapeutic strategies. Since Velcade (bortezomib) was approved for the treatment of relapsed/refractory MM in 2003, we have seen considerable improvement in extending MM patient survival. However, most patients a...
2022-02-21 | MTBLS3487 | MetaboLights
ProteomicsTDRD6 IP-MS data in mouse testis protein lysates
We immunoprecipitated endogenous TDRD6 from testis protein lysates of 28-day-old wild-type mice using our home-made TDRD6 antiserum. No TDRD6 protein was identified in Tdrd6-mutant mice carrying the p.G615X (GGG to TGA) variant. Thus, Tdrd6-mutant mice were utilized as negative control. A high-throu...
ORGANISM(S): Mus Musculus 
2023-05-11 | PXD042162 |
ProteomicsBRAF inhibitors enhance erythropoiesis and treat anemia through paradoxical activation of MAPK
Erythropoiesis is a crucial part in hematopoietic system, while facing disruptions from various diseases conditions. Anemia and blood shortages has become global challenges, with current finite pharmacological options like EPO or glucocorticoids having limitations, especially in genetic anemias like...
ORGANISM(S): Homo Sapiens 
2024-09-09 | PXD055730 |
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