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TranscriptomicsPotentiation of regulatory T cell stability and function via a neuropilin-1:semaphorin-4a axis
Regulatory T cells (Treg) represent a critical immunoregulatory component of the immune system. The signals that maintain Treg stability and potentiate their function remain obscure. Here we show that the immune cell surface ligand semaphorin-4a (Sema4a) Sema treated and NRP1 knock outs were compare...
ORGANISM(S): Mus musculus 
2013-09-06 | E-GEOD-41185 | biostudies-arrayexpress
UnknownEvaluating the potential for respiratory metagenomics to improve treatment of secondary infection and detection of nosocomial transmission on expanded COVID-19 intensive care units.
Not available
S-EPMC8594956 | biostudies-literature
TranscriptomicsRegulatory T cells require the phosphatase PTEN to restrain type 1 and follicular helper T-cell responses
The interplay between effector and regulatory T (Treg) cells is crucial for adaptive immunity, but how Treg control effector cell flexibility is elusive. We found that the phosphatase PTEN links Treg stability to the repression of TH1 and TFH (follicular helper) responses. Depletion of PTEN in Treg ...
ORGANISM(S): Mus musculus 
2015-01-05 | E-GEOD-63625 | biostudies-arrayexpress
UnknownThe ongoing Streptococcus pyogenes (Group A Streptococcus) outbreak in London, United Kingdom, in December 2022: a molecular epidemiology study.
Not available
S-EPMC10769882 | biostudies-literature
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