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ProteomicsMulti-omics analysis of Bordetella pertussis fermentation
Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our comprehensio...
ORGANISM(S): Bacteria Bordetella pertussis (strain Tohama I / ATCC BAA-589 / NCTC 13251) 
2023-03-11 | PXD039615 | Pride
Longitudinal multi-omics Virulence Fermentation molecular profiling Antigen production Proline starvation Bordetella pertussis Bacterial fermentation Cysteine starvation 
MetabolomicsDeep longitudinal multi-omics analysis of Bordetella pertussis cultivated in bioreactors highlights medium starvations and transitory metabolisms, associated to vaccine antigen biosynthesis variations and global virulence regulation

Bordetella pertussis is the bacterial causative agent of whooping cough, a serious respiratory illness. An extensive knowledge on its virulence regulation and metabolism is a key factor to ensure pertussis vaccine manufacturing process robustness. The aim of this study was to refine our ...

2023-02-21 | MTBLS5762 | MetaboLights
TranscriptomicsFlagellar export apparatus protein, FliH, is involved in post-transcriptional regulation of FlaB, motility and virulence of the relapsing fever spirochete Borrelia hermsii
Spirochetes are long, thin, motile, helical or flat wave bacteria that are unique among the prokaryotes by having flagella or axial filaments confined to an internal periplasmic space. These flagella are complex organelles that can play major roles in bacterial pathogenicity and are used as propelle...
ORGANISM(S): Borrelia hermsii 
2013-12-09 | E-GEOD-42863 | biostudies-arrayexpress
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