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TranscriptomicsExpression data from MMTV-PDK1 transgenic mice
The role of PDK1 on mammary tumorigenesis and its interaction with PPARdelta, was assessed. Transgenic mice were generated in which PDK1 was expressed in the mammary epithelium. We used microarrays to analyse global gene expression changes in MMTV-PDK1 transgenic mice versus wild-type mice and deter...
ORGANISM(S): Mus musculus 
2011-02-05 | E-GEOD-27083 | biostudies-arrayexpress
TranscriptomicsExpression data from MMTV-PPARd mice, 1 week GW501516 treatment
The role of murine peroxisome proliferator-activated receptor-delta (PPARd) in mammary tumorigenesis was assessed. Microarrays were used to analyse global gene expression to determine changes in MMTV-PPARd transgenic mice versus wild-type mice and the effect of GW501516. RNA was isolated (RNeasy Mi...
ORGANISM(S): Mus musculus 
2013-05-31 | E-GEOD-34109 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of human WPMY-1 cells treated with GW501516 ((a PPARbetadelta agonist) or TFGBeta2
Microarray analyses of WPMY-1

cells, either untreated (solvent) or treated with

GW501516 (0.3 µM), TGFBeta2 (10 ng/ml), or

both ligands for 6 h.
ORGANISM(S): Homo sapiens 
2010-07-21 | E-MEXP-2748 | biostudies-arrayexpress
UnknownA metabolomic study of the PPARδ agonist GW501516 for enhancing running endurance in Kunming mice.
Not available
S-EPMC4421799 | biostudies-literature
GenomicsRNA-Seq of Atlantic cod (Gadus morhua) liver treated with WY-14,643 and GW501516 in vivo
RNA-Seq of Atlantic cod (Gadus morhua) liver treated with WY-14,643 and GW501516 in vivo
PRJEB51137 | ENA
TranscriptomicsExpression data from MMTV-PPARd mice, 1 week GW501516 treatment
The role of murine peroxisome proliferator-activated receptor-delta (PPARd) in mammary tumorigenesis was assessed. Microarrays were used to analyse global gene expression to determine changes in MMTV-PPARd transgenic mice versus wild-type mice and the effect of GW501516.
ORGANISM(S): Mus musculus 
2013-05-31 | GSE34109 | GEO
TranscriptomicsTranscription profiling by array of human diploid lung fibroblasts exposed to TGFbeta2, GW501516 (a PPARbetadelta agonist) or both
Diploid human lung fibroblasts (WI-38 cells) were exposed to TGFbeta2 (inducing myofibroblast differentiation), GW501516 (a PPARbetadelta agonist) or both. Treated and control samples were hybridized against a reference sample made up of all samples pooled in equal parts and diluted by the number of...
ORGANISM(S): Homo sapiens 
2010-09-01 | E-MEXP-2750 | biostudies-arrayexpress
TranscriptomicsPPARM-NM-4 activation in human myotubes increases mitochondrial fatty acid oxidative capacity and reduces glucose utilization by a switch in substrate preference.
The role of peroxisome proliferator-activated receptor M-NM-4 (PPARM-NM-4) activation on global gene expression and mitochondrial fuel utilization were investigated in human myotubes. Only 21 genes were up-regulated and 3 genes were down-regulated after activation by the PPARM-NM-4 agonist GW501516....
ORGANISM(S): Homo sapiens 
2014-05-23 | E-GEOD-40789 | biostudies-arrayexpress
GenomicsEffect of PPARβ/δ agonist GW501516 on human and murine mesenchymal stromal cells
Effect of PPARβ/δ agonist GW501516 on human and murine mesenchymal stromal cells
PRJNA1192250 | ENA
TranscriptomicsExpression profiling, MDA-MB-231-luc2 response to GW501516
MDA-MB-231-luc2 cells were treated with the PPARd specific agonist GW501516 and the resulting expression changes profiled.
ORGANISM(S): Homo_sapiens 
2013-06-25 | E-MTAB-1262 | biostudies-arrayexpress
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