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TranscriptomicsComparison of gene expression in control and BRG1-knockdown H358 cell lines
Transcription was assessed in the human H358 NSCLC cell line after knockdown of BRG1, one of the mutually exclusive subunits of the SWI/SNF chromatin remodeling complex, by 2 different shRNAs. One biolgical replicate of each treatment; 4 technical replicates of each treatment.
ORGANISM(S): Homo sapiens 
2014-09-23 | E-GEOD-58542 | biostudies-arrayexpress
GenomicsHuman kinome CRISPR knockout screen in H358 parental and sotorasib resistant H358 cells
Human kinome CRISPR knockout screen in H358 parental and sotorasib resistant H358 cells
PRJNA1150241 | ENA
TranscriptomicsEffect of SRSF2 over-expression in a human lung carcinoma cell line
We showed that the over-expression of the SR protein SRSF2 led to the regulation of transcript abundance of many genes. H358 cell line with 6 samples with SRSF2 over-expression and 6 samples as control.
ORGANISM(S): Homo sapiens 
2013-08-30 | E-GEOD-50467 | biostudies-arrayexpress
ProteomicsGAPDH inhibition in A549 and H358 lung cancer cells
Human lung cancer cell lines A549 and H358 were obtained from (Biobank of Medical University of Graz) and cultured in RPMI 1640 (R0883; Sigma) supplemented with 10% fetal bovine serum (FBS; Gibco), 5 mM glutamine and 5 mM Pen Step, and sub-cultured regularly. For siRNA mediated knock-down of GAPDH, ...
ORGANISM(S): Homo sapiens (Human) 
2025-05-12 | PXD061610 | Pride
Human Koningic acid Gapdh 
OtherHuman kinome CRISPR knockout screen in H358 parental and sotorasib resistant H358 cells
A human kinome CRISPR knockout screen in H358 parental and sotorasib-R H358 cells using Addgene pooled libraries (#75314).
ORGANISM(S): Homo sapiens 
2025-10-07 | GSE275314 | GEO
GenomicsATAC-seq of NCI-H358 cells treated with KRAS G12C inhibitor sotorasib
ATAC-seq of NCI-H358 cells treated with KRAS G12C inhibitor sotorasib
PRJNA1106537 | ENA
TranscriptomicsDevelopment of acquired resistance to sotorasib in NCI-H358 cell line in vitro
NCI-H358 is a KRAS G12C-mutant non-small lung cancer cell line known to be sensitive to KRAS G12C-inhibitor sotorasib. Here, we aimed to develop sotorasib resistance in H358 and interrogate the resulting sotorasib-resistant cell line (H358-R). The H358-R cell line was created by continuous culturing...
ORGANISM(S): Homo sapiens 
2025-09-24 | GSE277630 | GEO
TranscriptomicsGene expression profiling of NSCLC cell lines upon TGFb-induced epithelial-mesenchymal transition (EMT)
Epithelial-mesenchymal transition has been implicated in tumor metastasis, cancer drug resistance and cancer stem cell features. In this study, we examined gene expression profiles of three non-small cell lung cancer cell lines, before and after experimentally induced EMT. We modeled epitheial-mese...
ORGANISM(S): Homo sapiens 
2014-11-19 | E-GEOD-49644 | biostudies-arrayexpress
GenomicsExpression data from CHST11 over-expression in A-549 or NCI-H358 cells
Expression data from CHST11 over-expression in A-549 or NCI-H358 cells
PRJNA545431 | ENA
GenomicsATAC-seq of sotorasib-resistant H23 and H358 cells treated with TEAD inhibitor GNE-7883
ATAC-seq of sotorasib-resistant H23 and H358 cells treated with TEAD inhibitor GNE-7883
PRJNA952671 | ENA
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