Sort   by:  
 Page size 
UnknownTales of a Super Butterfly: Is Vanessa carye a Truly Migrant Species? Unraveling Migration Using Morphological and Genomics Approaches.
Not available
S-EPMC12449186 | biostudies-literature
ProteomicsA lineage master regulator and cancer-selective partner transcription factor reprogram 3D chromatin topology to establish tumor-specific gene control
Lineage-determining transcription factors (TFs), such as p63 in epithelial tissues, establish normal tissue identity but can also drive carcinogenesis. The epigenetic basis for these divergent effects, however, is unclear. Here, we show that p63 reorganizes three-dimensional (3D) chromatin topology ...
ORGANISM(S): Homo sapiens (Human) 
2026-09-14 | PXD073599 | Pride
P63 foxk1 
TranscriptomicsRetinoid X Receptor activation reverses the age-related deficiency in myelin debris phagocytosis and enhances remyelination
The efficiency of central nervous system (CNS) remyelination declines with age. This is in part due to an age-associated decline in the phagocytic removal of myelin debris, which contains inhibitors of oligodendrocyte progenitor cell differentiation. In this study we show that expression of genes i...
ORGANISM(S): Homo sapiens 
2015-11-04 | E-GEOD-66988 | biostudies-arrayexpress
TranscriptomicsDecay-initiating endoribonucleolytic cleavage by RNase Y is kept under tight control via sequence preference and sub-cellular localisation
Bacteria depend on efficient RNA turnover to rapidly alter gene expression, essentially for responding to changing conditions. Nevertheless, remarkably few details are known about the rate-limiting steps in targeting and decay of RNA. The membrane-anchored endoribonuclease RNase Y is a virulence fac...
ORGANISM(S): Staphylococcus aureus 
2015-09-01 | E-GEOD-68811 | biostudies-arrayexpress
TranscriptomicsOvercoming cetuximab resistance in HNSCC: The role of AURKB and DUSP proteins
Unraveling the underlying mechanisms of cetuximab resistance in head and neck squamous cell carcinoma (HNSCC) is of major importance as many tumors remain non-responsive or become resistant. Out microarray results suggest that resistant cells still exhibit RAS-MAPK pathway signaling contributing to ...
ORGANISM(S): Homo sapiens 
2014-09-18 | E-GEOD-61495 | biostudies-arrayexpress
TranscriptomicsCross-regulation between the response regulators PhoB and TctD allows for the integration of diverse environmental signals in Pseudomonas aeruginosa
Two-component systems (TCS) serve as basic stimulus-response coupling mechanisms to allow organisms to sense and respond to a large variety of environmental conditions. In the opportunistic pathogen Pseudomonas aeruginosa, more than 100 genes encode TCS components. To avoid unwanted cross-talk betwe...
ORGANISM(S): Pseudomonas aeruginosa UCBPP-PA14 
2015-06-08 | E-GEOD-64056 | biostudies-arrayexpress
ProteomicsLarge-scale Multi-omic Analysis of COVID-19 Severity
We performed RNA-Seq and high-resolution mass spectrometry on 128 blood samples from COVID-19 positive and negative patients with diverse disease severities. Over 17,000 transcripts, proteins, metabolites, and lipids were quantified and associated with clinical outcomes in a curated relational datab...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2020-07-08 | MSV000085703 | MassIVE
Sort   by:  
 Page size