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TranscriptomicsGene expression profiling of patients from the Danish Center for Translational Breast Cancer Research program
Female breast cancer patients who underwent surgery for breast cancer as part of the Danish Center for Translational Breast Cancer Research program were included from 2003 to 2012. Patient inclusion criteria were: (1) a unifocal tumor with an estimated size of more than 20 mm in diameter, (2) none o...
ORGANISM(S): Homo sapiens 
2018-11-16 | E-MTAB-7201 | biostudies-arrayexpress
TranscriptomicsmRNA profiling of pre- and postoperative breast tumors
Gene expression studies on breast cancer have generally been performed on tissue obtained at the time of surgery. Overexpression of several genes may be a result of surgical trauma or preoperative manipulation, and may not reflect any biological impact of the disease. This study compares the express...
ORGANISM(S): Homo sapiens 
2011-03-01 | E-MTAB-470 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation profiles in progression to in situ and invasive carcinoma of the breast with impact on gene transcription and prognosis
Ductal carcinoma in situ (DCIS) of the breast is a precursor of invasive breast carcinoma (IBC). DNA methylation alterations are thought to be an early event in progression of cancer, and may prove valuable as a tool in clinical decision making and for understanding neoplastic development. Genome-wi...
ORGANISM(S): Homo sapiens 
2014-08-08 | E-GEOD-60185 | biostudies-arrayexpress
TranscriptomicsMammographic density and genetics - A study of breast biopsies in relation to mammoraphic density
Introduction Mammographic density (MD), as assessed from film screen mammograms, is determined by the relative content of adipose, connective and epithelial tissue in the female breast. In epidemiological studies, a high percentage of MD confers a four to six fold risk elevation of developing breast...
ORGANISM(S): Homo sapiens 
2010-08-13 | E-GEOD-18672 | biostudies-arrayexpress
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