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MetabolomicsNQO1 protects obese mice through improvements in glucose and lipid metabolism.
Chronic nutrient excess leads to metabolic disorders and insulin resistance. Activation of stress-responsive pathways via Nrf2 activation contributes to energy metabolism regulation. Here, inducible activation of Nrf2 in mice and transgenesis of the Nrf2 target, NQO1, conferred protection from diet-...
2024-05-23 | MTBLS2085 | MetaboLights
ProteomicsPLpro inhibition protects in post-acute sequelae mouse model of COVID-19
The COVID-19 pandemic has highlighted how vulnerable a globally connected population is to the threat of newly emerging zoonotic viruses, exemplified by SARS-CoV-2. Despite considerable efforts to identify antivirals for coronaviruses (CoVs) in the last two decades, there exists only one FDA-approve...
ORGANISM(S): Mus musculus (Mouse) 
2025-02-23 | PXD054356 | Pride
Sars-cov-2  long covid  pasc  inflammation 
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of DLD-1 and MDA-MB-231 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). This dataset also includes DLD-1 cells treated with FT671 (USP7 inhibitor) at 10 µM for 30 min and 6 h.Sample IDs:#1-5 Control 30 ...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073869 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of UO-31 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). Sample IDs:#1-5 Control 30 min UO-31#6-10 WEHI-092 30 min UO-31#11-15 Control 360 min UO-31#16-20 WEHI-092 360 min UO-31#21-25 Control 24 h UO-31...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073754 | Pride
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
K-GG ubiquitin profiling of SK-MEL-2 and UO-31 cells treated with the selective USP9X inhibitor WEHI-092 at 10 µM for 30 min, 6 h, and 24 h (and DMSO-treated control). This dataset is the matched global quantitative proteomics data.Sample IDs:#1-5 Control 30 min UO-31#6-10 WEHI-092 30 min UO-31#11-1...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD073798 | Pride
MetabolomicsGNPS - Schizophrenia Plasma Metabolome Analysis
Metabolomics analysis of plasma collected from patients with schizophrenia and non-psychiatric control subjects.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-02 | MSV000086975 | GNPS
UnknownPreexposure chemoprophylaxis for HIV prevention in men who have sex with men.
Not available
S-EPMC3079639 | biostudies-literature
MetabolomicsResolving coral photoacclimation dynamics through coupled photophysiological and metabolomic profiling
Corals continuously adjust to short term variation in light availability on shallow reefs. Long-term light alterations can also occur due to natural and anthropogenic stressors, as well as management interventions such as coral transplantation. Although short term photophysiological responses are re...
2019-04-11 | MTBLS768 | MetaboLights
ProteomicsSchizophrenia Proteome Data High Resolution Method
PTM-tolerant quantitative proteome analysis of plasma collected from schizophrenia patients and nonspychiatric healthy controls.
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2021-03-02 | MSV000086977 | MassIVE
ProteomicsGlobal analysis of cancer cell responses to USP9X inhibition
Global proteomics experiment using USP9X siRNA (and control) MDA-MB-231 cells with (10 µM, 24 h) and without USP9X inhibitor treatment using WEHI-092 and untreated (DMSO) control (P5448, see sample key). Global proteomics experiment profiling cancer cell lines treated with USP9X inhibitor WEHI-092 (...
ORGANISM(S): Homo sapiens (Human) 
2026-04-09 | PXD062674 | Pride
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