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MetabolomicsFecal microbiota transplantation plus anti-PD-1 immunotherapy in advanced melanoma: a phase I trial

Fecal microbiota transplantation (FMT) represents a potential strategy to overcome resistance to immune checkpoint inhibitors in patients with refractory melanoma; however, the role of FMT in first-line treatment settings has not been evaluated. We conducted a multicenter phase I trial combining ...

2025-02-27 | MTBLS711 | MetaboLights
GenomicsChIP-seq for Prep on whole zebrafish embryos at 3.5 and 12hpf
Prep ChIP-seq on whole zebrafish embryos at 3.5 and 12 hours post fertilisation (hpf)
ORGANISM(S): Danio rerio 
2018-06-25 | E-MTAB-5967 | biostudies-arrayexpress
TranscriptomicsRNA-seq of wild-type zebrafish embryos developmentally exposed to three addictive drugs
RNA-seq of wild-type Tüpfel long fin (TLF) zebrafish embryos developmentally exposed to three addictive drugs - 5 µM nicotine, 1.14 µM oxycodone and 5 µM amphetamine. Each of the 24 samples (6 samples per drug, plus 6 control samples) represents RNA from a pool of seven 5 dpf zebrafish embryos, expo...
ORGANISM(S): Danio rerio 
2022-01-24 | E-MTAB-11086 | biostudies-arrayexpress
TranscriptomicsRNA-seq of zebrafish embryos with mutations in a muscle-specific kinase and the giant titin protein
RNA-seq of zebrafish embryos with mutations in srpk3 (sa1890 allele) and/or ttn.1 (sa5562 allele). Each of the 24 samples (six samples for each of four genotypes) represents RNA from a pool of three 5 dpf zebrafish embryos.
ORGANISM(S): Danio rerio 
2024-02-09 | E-MTAB-12934 | biostudies-arrayexpress
GenomicsChIP-seq for NF-YA and Pbx4 on whole zebrafish embryos at 3.5hpf
NF-YA and Pbx4 ChIP-seq on pooled whole zebrafish embryos at 3.5 hours post fertilisation (hpf)
ORGANISM(S): Danio rerio 
2020-04-28 | E-MTAB-8137 | biostudies-arrayexpress
TranscriptomicsTranscription profiling by array of Danio rerio fast skeletal muscle from fish fed a single satiating meal
The F5 generation of a wild-caught population of zebrafish (Danio rerio) from Mymensingh, Bangladesh, were used in this study. Replicate experiments were carried out with adult male fish aged 9 months. Each group was maintained in a 50L tank at 27M-11.5M-:C and 12:12h dark:light photoperiod and fed...
ORGANISM(S): Danio rerio 
2011-03-11 | E-MEXP-2887 | biostudies-arrayexpress
TranscriptomicsBaseline expression from transcriptional profiling of zebrafish developmental stages
Establish baseline expression transcriptional signatures for zebrafish developmental stages. Total RNA was extracted from single wild type zebrafish embryos at a series of different developmental stages. RNA from 12 embryos was pooled to generate a replicate.The RNA was DNase treated. Stranded RNAs...
ORGANISM(S): Danio rerio 
2016-06-12 | E-ERAD-475 | biostudies-arrayexpress
UnknownPreferences, barriers and facilitators regarding virtual pelvic healthcare in individuals with gynaecological cancers: protocol for a patient-oriented, mixed-methods study.
Not available
S-EPMC9884898 | biostudies-literature
TranscriptomicsGenome-wide mapping of Hif-1α binding sites in zebrafish [microarray]
Analysis of gene expression changes in the von Hippel Lindau when mutant compared to wild-type at 4dpf using a whole genome microarray expression profiling. The von Hippel Lindau mutant displays a systemic hypoxic response under normoxic conditions. We performed single-colour microarrays to identify...
ORGANISM(S): Danio rerio 
2016-03-22 | E-GEOD-70885 | biostudies-arrayexpress
GenomicsGenome-wide mapping of Hif-1α binding sites in zebrafish [ChIP-seq]
Analysis of the binding sites of Hif-1α in both wild-type and von Hippel Lindau mutant zebrafish lines at 4dpf by ChIP linked next generation sequencing. The von Hippel Lindau mutant displays a systemic hypoxic response under normoxic conditions. Results show the extent of Hif-1α binding to the ge...
ORGANISM(S): Danio rerio 
2016-03-22 | E-GEOD-70727 | biostudies-arrayexpress
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