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TranscriptomicsChIP-seq against the CTCF protein in Raji cells with inducible BZLF1 protein (KF717093.1) prior to and post induction of BZLF1.
Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4; GenBank accession KF717093.1) genome.
ORGANISM(S): Homo sapiens 
2019-04-01 | E-MTAB-7787 | biostudies-arrayexpress
GenomicsChIP-seq analysis with an antibody directed against the human Rad21 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1.
Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4; GenBank accession KF717093.1) genome.
ORGANISM(S): Homo sapiens 
2021-06-22 | E-MTAB-8424 | biostudies-arrayexpress
GenomicsChIP-seq analysis with an antibody directed against the human H3K4me1 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1.
Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4 GenBank accession KF717093.1) genome.
ORGANISM(S): Homo sapiens 
2021-02-07 | E-MTAB-8425 | biostudies-arrayexpress
GenomicsChIP-seq analysis with an antibody directed against the human H3K4me3 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1.
Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4; GenBank accession KF717093.1) genome.
ORGANISM(S): Homo sapiens 
2021-06-22 | E-MTAB-8419 | biostudies-arrayexpress
TranscriptomicsChIP-seq analysis with an antibody directed against the H3K27me3 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1.
Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4; GenBank accession KF717093.1) genome.
ORGANISM(S): Homo sapiens 
2021-06-22 | E-MTAB-8423 | biostudies-arrayexpress
TranscriptomicsChIP-seq analysis with an antibody directed against the human SMC1 protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1
Peaks were identified in both the human and viral (EBV (Human Herpesvirus 4; GenBank accession KF717093.1) genome.
ORGANISM(S): Homo sapiens 
2021-06-22 | E-MTAB-8428 | biostudies-arrayexpress
TranscriptomicsChIP-seq analysis with an antibody directed against the human H3K27ac protein in Raji cells (Genbank: KF717093.1) prior to and post induction of BZLF1.
ChIP peaks were identified in both the human and viral genomes (genome assembly GRCh37 (hg19) and Epstein-Barr virus, Human Herpesvirus 4; GenBank accession KF717093.1).
ORGANISM(S): Homo sapiens 
2021-06-22 | E-MTAB-8421 | biostudies-arrayexpress
TranscriptomicsRNA-seq in Raji cells with inducible BZLF1 prior to and after induction of EBV's lytic cycle by doxycycline
(i) RNA transcripts of Raji iBZLF1 cells (https://www.biorxiv.org/content/10.1101/573659v1) were compared between non-induced cells and cells induced with doxycycline (100 ng/ ml) for 6 h. Human (Hg19) as well as viral (EBV, Raji KF717093.1) transcripts were analyzed. Artificial ERCC Spike-ins (Ther...
ORGANISM(S): Homo sapiens 
2019-01-01 | E-MTAB-7820 | biostudies-arrayexpress
TranscriptomicsChIP-seq against BZLF1 in DG75 cells (EBV-negative, human Burkitt lymphoma cell line)
The parental DG75 cell line is EBV negative and cannot express the viral BZLF1 protein, thus, this set of experiments served as a negative control. After ChIP, peaks were identified in both the human and viral (EBV (Human Herpesvirus 4) genome KF717093.1) genome. Only few peaks were identified. Expe...
ORGANISM(S): Homo sapiens 
2019-04-05 | E-MTAB-7821 | biostudies-arrayexpress
TranscriptomicsInfection of naïve primary human B-lymphocytes with Epstein-Barr virus (EBV) – time course transcriptomic analysis in the pre-latent phase of viral infection
B cells from anonymous adenoid donors were isolated and sorted for naïve B cells, which were subsequently infected with a reference EBV strain (2089_B95-8) using a defined multiplicity of infection. Infection of resting B cells with EBV induces their activation, their proliferation, and subsequent i...
ORGANISM(S): Homo sapiens 
2019-07-01 | E-MTAB-7805 | biostudies-arrayexpress
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