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TranscriptomicsHeme utilization in the Caenorhabditis elegans hypodermal cells is facilitated by HRG-2
The roundworm Caenorhabditis elegans is a heme auxotroph that requires the coordinated actions of HRG-1 heme permeases to transport environmental heme into the intestine and HRG-3, a secreted protein, to deliver intestinal heme to other tissues including the embryo. Here we show that heme homeostas...
ORGANISM(S): Caenorhabditis elegans 
2013-01-01 | E-GEOD-34471 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of C. elegans reveals heme homeostasis is regulated by the conserved and concerted functions of HRG-1 proteins
Hemes are essential but potentially cytotoxic cofactors that participate in critical and diverse biological processes. Although the pathway and intermediates for heme biosynthesis have been well defined, the intracellular networks which mediate heme trafficking remain unknown. Caenorhabditis e...
ORGANISM(S): Caenorhabditis elegans 
2008-10-18 | E-GEOD-8696 | biostudies-arrayexpress
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