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TranscriptomicsGene Expression and Exon Splicing Change Analysis of Mouse N2A Cell Transcriptome upon Polypyrimidine tract-binding protein depletion.
Purpose : Splicing factors regulate splice site choices in pre-mRNA and determine final exon set in mRNA. To understand mechanisms of splicing regulation, it is important to identify and characterize exon targets of splicing factors. Recently, development of RNA-seq technology enables researchers to...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-45119 | biostudies-arrayexpress
TranscriptomicsAlternative splicing in PTBP2 knockout mouse brain
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-51740 | biostudies-arrayexpress
TranscriptomicsMicroarray analysis of alternative splicing in PTBP2 knockout mouse brain
The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. The splicing regulatory proteins PTBP1 and PTBP2 show distinct temporal expression profiles in the developing brain. Neuronal progenitor cells predominantly express PTBP1, whereas developing neuro...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-51738 | biostudies-arrayexpress
TranscriptomicsRNAseq analysis of alternative splicing in PTBP2 knockout mouse brain
The splicing regulator PTBP2 controls a program of embryonic splicing required for neuronal maturation. The splicing regulatory proteins PTBP1 and PTBP2 show distinct temporal expression profiles in the developing brain. Neuronal progenitor cells predominantly express PTBP1, whereas developing neuro...
ORGANISM(S): Mus musculus 
2013-12-01 | E-GEOD-51733 | biostudies-arrayexpress
TranscriptomicsRegulation of Lin28b and let-7 in developmental myelopoiesis
We isolated RNA from sorted common myeloid progenitor cells from wild-type fetal liver, wild-type adult bone marrow, transgenic Lin28b bone marrow, let-7b/c knock-out bone marrow, and Lin28b-deficient fetal liver and compared mRNA expression profiles. Examination of mRNA expression in common myeloid...
ORGANISM(S): Mus musculus 
2016-06-26 | E-GEOD-72521 | biostudies-arrayexpress
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