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TranscriptomicsHOTAIR reprograms gene expression profiling in esophageal squamous cell carcinoma (ESCC) KYSE180 cells
To investigate the functional role of HOTAIR in esophageal squanmous cell carcinoma (ESCC) cells, RNAi-mediated knockdown of HOTAIR and overexpression of HOTAIR were carried out using KYSE180 cells. Gene expression microarray analysis revealed that a number of reported HOTAIR target genes were regul...
ORGANISM(S): Homo sapiens 
2013-06-05 | E-GEOD-47638 | biostudies-arrayexpress
TranscriptomicsKYSE180 cells transfected with HOTAIR compared to control cells
This SuperSeries is composed of the SubSeries listed below. Refer to individual Series
ORGANISM(S): Homo sapiens 
2013-06-05 | E-GEOD-47639 | biostudies-arrayexpress
TranscriptomicsGenome-wide DNA methylation profiling of KYSE180 cells transfected with HOTAIR vector using Illumina HumanMethylation 450 arrays
To analysis of the effect of HOTAIR on global DNA methylation in KYSE180 esophageal cancer cell line, genome-scale DNA methylation was analyzed in a pair of esophageal cancer cell lines, KYSE180 cells stably transfected with HOTAIR and control KYSE180 cells. The results from genome-wide DNA methylat...
ORGANISM(S): Homo sapiens 
2013-06-05 | E-GEOD-47637 | biostudies-arrayexpress
TranscriptomicsExpression profile of PBMCs following decitabine treatment
The epigenetic regulation, for example, DNA methylation, controls the development and differentiation of both tumor cells and immunocytes. Treatment with DNA demethylating agent (such as decitabine) has shown a dramatic clinical benefit in hematological malignancies and solid tumors. However, the in...
ORGANISM(S): Homo sapiens 
2016-06-30 | E-GEOD-72686 | biostudies-arrayexpress
MetabolomicsA metabolome atlas of mouse brain on the global metabolic signature dynamics following short-term fasting
Calorie restriction (CR) or a fasting regimen is considered one of the most potent non-pharmacological interventions to prevent chronic metabolic disorders, ameliorate autoimmune diseases, and attenuate aging. Despite efforts, the mechanisms by which CR improves health, particularly brain health, ar...
2025-07-31 | MTBLS8006 | MetaboLights
TranscriptomicsGlobal expression analysis of miR-32/455/181a/181b overexpression or PI3K knockdown in KYSE30 cells
Analysis of the effect of the miRNA set (miR-32/455/181a/181b) on global gene expression. The hypothesis tested was that overexpression of these miRNAs would produce changes in gene expression similar to changes caused by PI3K knockdown. Data provided insight into genes that are disrupted with eithe...
ORGANISM(S): Homo sapiens 
2012-12-29 | E-GEOD-43195 | biostudies-arrayexpress
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