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ProteomicsUrinary proteomics investigations into contrast-induced acute kidney injury
The incidence of CI-AKI varies from 5% to 20% among hospitalized patients. However, research on the pathophysiological mechanism and biomarkers of CI-AKI has not been deep so far, especially research with LC-MS/MS methods. MS has brought proteomics research into the modern era and continues to be th...
ORGANISM(S): Homo Sapiens 
2021-02-21 | PXD024271 |
MetabolomicsHost specific sphingomyelin is critical for replication of diverse RNA viruses
Lipids and lipid metabolism play an important role in RNA virus replication, which typically occurs on host cell endomembrane structures in the cytoplasm through mechanisms that are not yet fully identified. We conducted genome-scale CRISPR screening and identified sphingomyelin synthase 1 (SMS1; en...
2026-10-29 | MTBLS11308 | MetaboLights
TranscriptomicsComprehensive mutational analysis of primary and relapse acute promyelocytic leukemia
Acute promyelocytic leukemia (APL) is a subtype of myeloid leukemia characterized by differentiation block at the promyelocyte stage. Besides the presence of chromosomal rearrangement t(15;17) leading to formation of PML-RARA fusion, other genetic alterations have also been implicated in APL. ...
ORGANISM(S): Homo sapiens 
2016-02-17 | E-GEOD-77946 | biostudies-arrayexpress
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