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GenomicsScl specifies hemogenic endothelium and inhibits cardiogenesis via primed enhancers [ChIP-seq]
Scl/Tal1 confers hemogenic competence and prevents cardiomyogenesis in embryonic endothelium. Here we show that Scl both directly activates a broad gene regulatory network required for hematopoietic stem/progenitor cell (HS/PC) development, and represses transcriptional regulators required for cardi...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-47082 | biostudies-arrayexpress
TranscriptomicsRegulatory complexity revealed by integrated cytological and RNA-seq analyses of meiotic substages in mouse spermatocytes
The juvenile onset of spermatogenesis in mice is analyzed by combining cytological and transcriptomic data in a novel computational analysis, resulting in meiotic substage-specific transcriptomes and the discovery of a transcription factor network that regulates the substages of meiosis. Germ cells ...
ORGANISM(S): Mus musculus 
2016-08-24 | E-GEOD-72833 | biostudies-arrayexpress
TranscriptomicsScl specifies hemogenic endothelium and inhibits cardiogenesis via primed enhancers [RNA-seq]
Scl/Tal1 confers hemogenic competence and prevents cardiomyogenesis in embryonic endothelium. Here we show that Scl both directly activates a broad gene regulatory network required for hematopoietic stem/progenitor cell (HS/PC) development, and represses transcriptional regulators required for cardi...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-47083 | biostudies-arrayexpress
GenomicsScl specifies hemogenic endothelium and inhibits cardiogenesis via primed enhancers [RRBS]
Scl/Tal1 confers hemogenic competence and prevents cardiomyogenesis in embryonic endothelium. Here we show that Scl both directly activates a broad gene regulatory network required for hematopoietic stem/progenitor cell (HS/PC) development, and represses transcriptional regulators required for cardi...
ORGANISM(S): Mus musculus 
2015-01-01 | E-GEOD-56359 | biostudies-arrayexpress
TranscriptomicsATAC-seq on endocardial cells from E12.5 mouse hearts in Tbx20 knockouts and wild type counterparts
We used ATAC-seq (Buenrostro et al, 2013) to identify regions of open chromatin in FACS sorted mouse endothelial cells from E12.5 hearts. Please note that the animals were injected at different dates, which resulted in different effects of the knockout, as indicated in the batch attribute of the s...
ORGANISM(S): Mus musculus 
2017-06-02 | E-MTAB-3972 | biostudies-arrayexpress
TranscriptomicsComparison of transcriptomes between Marf1+/+ (WT) and Marf1 ENU/ENU (Mutant) fully-grown oocytes (FGO)
Marf1 (MUT) female mice are infertile and the meiosis of the oocytes are arrest at prophase I. We thought to identify the potential causes of the meiotic arrest phenotype in the mutant oocytes by comparing the transcriptomes of the WT and mutant fully-grown oocytes (from 23-d old mice) that are tran...
ORGANISM(S): Mus musculus 
2012-03-30 | E-GEOD-31985 | biostudies-arrayexpress
UnknownAge and Genetic Background Modify Hybrid Male Sterility in House Mice.
Not available
S-EPMC7536842 | biostudies-literature
UnknownOldest skeleton of a fossil flying squirrel casts new light on the phylogeny of the group.
Not available
S-EPMC6177260 | biostudies-literature
UnknownCharacterization of the complete plastome of Elymus tangutorum (Poaceae: Triticeae).
Not available
S-EPMC7707338 | biostudies-literature
TranscriptomicsComparative gene expression analysis of repro9/repro9 and wild type testes from 14 and 17 day mice
Repro9 in an allele of Mybl1 (A-Myb) transcription factor obtained in ENU screen to identify alleles causing mouse infertility. Repro9/repro9 mutant males are infertile due to meiotic arrest at pachytene stage. Mutants show wide range of abnormalities including inefficient chromosome synapsis, sex b...
ORGANISM(S): Mus musculus 
2011-10-18 | E-GEOD-28025 | biostudies-arrayexpress
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