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MetabolomicsUntargeted metabolomic analysis of human milk from healthy mothers reveals drivers of metabolite variability.
Understanding the human milk metabolome can help inform infant nutrition and health. Untargeted metabolomics was used to study breast milk from 31 healthy participants to assess the shared metabolites in milk from participants with various backgrounds and understand how different demographic, health...
2024-10-04 | MTBLS2419 | MetaboLights
TranscriptomicsSequencing of HSV-1 genomic DNA to identify genomic variation resulting from selective pressure imposed by mutation of the PP1 binding site in the pUL21 gene
The pUL21 gene is essential for efficient replication and dissemination in herpes simplex virus 1 (HSV-1) but the molecular basis for its function is not well understood. Experimental work revealed that pUL21 is a virus-encoded adaptor of protein phosphatase 1 (PP1). Mutation of the specific motif i...
ORGANISM(S): Human alphaherpesvirus 1 
2021-07-31 | E-MTAB-10788 | biostudies-arrayexpress
TranscriptomicsInactivation of the GacA response regulator in Pseudomonas fluorescens Pf-5 has far-reaching transcriptomic consequences
The GacS/GacA signal transduction system is a central regulator in Pseudomonas spp., including the biological control strain P. fluorescens Pf-5, in which GacS/GacA controls the production of secondary metabolites and exoenzymes that suppress plant pathogens. A whole genome oligonucleotide microarra...
ORGANISM(S): Pseudomonas fluorescens Pf-5 
2010-03-03 | E-GEOD-16898 | biostudies-arrayexpress
TranscriptomicsPtrA is required for coordinate regulation of gene expression during phosphate depletion in a marine Synechococcus
The genome of the marine Synechococcus sp. WH8102 displays a minimal regulatory network yet physiological and molecular responses of this organism are tuned to episodic limitation for nitrogen and phosphorus. Microarray analyses have demonstrated a key role for the two-component regulatory system, P...
ORGANISM(S): Synechococcus sp. WH 8102 
2010-04-08 | E-GEOD-18511 | biostudies-arrayexpress
TranscriptomicsGene expression response to copper toxicity between coastal and open ocean strains of marine Synechococcus
Marine cyanobacteria are thought to be the most sensitive of the phytoplankton groups to copper toxicity, yet little is known of the transcriptional response of marine Synechococcus to copper shock. Global transcriptional response to two levels of copper shock was assayed in both a coastal and an o...
ORGANISM(S): Synechococcus sp. CC9311 
2010-05-17 | E-GEOD-13910 | biostudies-arrayexpress
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