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TranscriptomicsPolycomb repressive complex 2-dependent and M-bM-^@M-^Sindependent functions of Jarid2 in transcriptional regulation in Drosophila [Affymetrix]
Jarid2 was recently identified as an important component of the mammalian Polycomb Repressive Complex 2 (PRC2), where it has a major effect on PRC2 recruitment in mouse embryonic stem cells. Although Jarid2 is conserved in Drosophila, it has not previously been implicated in Polycomb (Pc) regulation...
ORGANISM(S): Drosophila melanogaster 
2012-02-23 | E-GEOD-36038 | biostudies-arrayexpress
GenomicsPolycomb repressive complex 2-dependent and -independent functions of Jarid2 in transcriptional regulation in Drosophila [ChIP-Seq]
Jarid2 was recently identified as an important component of the mammalian Polycomb Repressive Complex 2 (PRC2), where it has a major effect on PRC2 recruitment in mouse embryonic stem cells. Although Jarid2 is conserved in Drosophila, it has not previously been implicated in Polycomb (Pc) regulation...
ORGANISM(S): Drosophila melanogaster 
2012-02-23 | E-GEOD-33546 | biostudies-arrayexpress
TranscriptomicsArgonaute2 mediates compensatory expansion of the pancreatic M-CM-^_-cell
Pancreatic M-CM-^_-cells adapt to compensate for the increased metabolic demand during insulin resistance. While the microRNA pathway has an essential role in the expansion of M-CM-^_-cell mass, the extent of its contribution is unclear. Here we show that miR-184 is silenced in the pancreatic islets...
ORGANISM(S): Mus musculus 
2014-02-06 | E-GEOD-46623 | biostudies-arrayexpress
TranscriptomicsTranscription profiling of human cells expressing FoxM1-ER fusion protein
Experiment description To identify FoxM1-regulated genes, we carried out gene expression profile analysis after inducible activation of a FoxM1-ER fusion protein using high-density human cDNA microarrays. We constructed a stable line of U2OS cells expressing full-length HA-FoxM1 fused at its C-term...
ORGANISM(S): Homo sapiens 
2005-01-01 | E-MEXP-230 | biostudies-arrayexpress
TranscriptomicsDeciphering the Wnt-dependent gene signature in colorectal cancer cells
Microarray-based gene expression data were generated from RNA from Ls174T colorectal carcinoma cell lines in which Wnt-dependent transcriptional activity can be abrogated by inducible overexpression of a dominant-negative form of Tcf4 or siRNA against M-NM-2-catenin. shRNA against M-NM-2-catenin, or...
ORGANISM(S): Homo sapiens 
2011-11-29 | E-GEOD-18560 | biostudies-arrayexpress
UnknownVisual tuning in the flashlight fish Anomalops katoptron to detect blue, bioluminescent light.
Not available
S-EPMC6040694 | biostudies-literature
UnknownMicrobial functional changes mark irreversible course of Tibetan grassland degradation.
Not available
S-EPMC9106683 | biostudies-literature
TranscriptomicsIdentification of genes specific to mouse primordial germ cells through dynamic global gene expression
The molecular mechanisms underlying the commitment of cells to the germ cell lineage and the subsequent formation of germ cells during mammalian development remain poorly understood due to an inability to obtain sufficient amounts of cellular materials to conduct thorough in-vitro analyses. Although...
ORGANISM(S): Mus musculus 
2010-11-16 | E-GEOD-23322 | biostudies-arrayexpress
UnknownMethylation of lysine 9 in histone H3 directs alternative modes of highly dynamic interaction of heterochromatin protein hHP1β with the nucleosome.
Not available
S-EPMC3460472 | biostudies-literature
UnknownAcetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling.
Not available
S-EPMC10850750 | biostudies-literature
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