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DNA interstrand crosslinks (ICLs) block replication fork progression by inhibiting DNA strand separation. Repair of ICLs requires sequential incisions, translesion DNA synthesis, and homologous recombination, but the full set of factors involved in these transactions remains unknown. Here we establi...
ORGANISM(S): Homo Sapiens (ncbitaxon:9606) 
2016-03-13 | MSV000079577 | MassIVE
To develop a classifier based on microRNAs for primary tumor site identification of liver core biopsies and to explore the influence of surrounding normal liver tissue on classification. Tissue samples from 333 patients, corresponding to one of the following ten assay classes, were obtained from arc...
ORGANISM(S): Homo sapiens 
Total RNA from testicular tissue histologically scored as containing carcinoma in situ (CIS) in 50%, 75%, and 100% of the seminiferous tubules and total RNA from testicular tissue with preserved normal and complete spermatogenesis and no CIS present were isolated, amplified, labeled, and co-hybridiz...
ORGANISM(S): Homo sapiens 
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