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MetabolomicsTargeting the SREBP-dependent lipidomic reprogramming by virus infection for broad-spectrum therapeutic intervention
Viruses are obligate intracellular parasites that exploit the host metabolic machineries to meet their extraordinary biosynthetic demands. Integrative transcriptomic and lipidomic profiling confirmed that Middle East respiratory syndrome coronavirus (MERS-CoV) infection reprograms the host lipid met...
2018-11-26 | MTBLS762 | MetaboLights
UnknownMolecular epidemiological study of hepatitis B virus in blood donors from five Chinese blood centers.
Not available
S-EPMC3431469 | biostudies-literature
ProteomicsSpatiotemporal and global profiling of DNA-protein interactions enables discovery of low-affinity transcription factors
Precise dissection of DNA-protein interactions is essential for elucidating recognition basis, dynamics, and gene regulation mechanism. However, global profiling of weak and dynamic DNA-protein interactions remains a long-standing challenge. Here, we establish light-induced lysine (K) enabled crossl...
ORGANISM(S): Homo Sapiens 
2023-01-03 | PXD039229 |
ProteomicsAfter enriching U251 cell lysate by a lactic probe with a photo-cross linker and a corresponding control probe without lactic modification to find related reader or eraser, the protein enriched were identified by Lc-MS (three replicates)
In brief, U251 cells lysate were incubated with 10μM KpKla and 10μM KpKla separately. After incubating for 1h at 37℃, the solutions were irradiated by 365nm UV for 5 min on ice. Then CuSO4, THPTA (tris-hydroxypropyltriazolylmethylamine), TCEP (tris(2-carboxyethyl)phosphine) and biotin azide were add...
ORGANISM(S): Homo Sapiens 
2023-01-29 | PXD039731 |
UnknownFamilial chordoma: A case report and review of the literature.
Not available
S-EPMC4665336 | biostudies-literature
UnknownMaternal circadian disruption is associated with variation in placental DNA methylation.
Not available
S-EPMC6485638 | biostudies-literature
UnknownGeneration of biallelic knock-out sheep via gene-editing and somatic cell nuclear transfer.
Not available
S-EPMC5031972 | biostudies-literature
UnknownQuick Commitment and Efficient Reprogramming Route of Direct Induction of Retinal Ganglion Cell-like Neurons.
Not available
S-EPMC7663790 | biostudies-literature
UnknownHigh-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: a pilot, randomized, double-blind, placebo-controlled trial.
Not available
S-EPMC3417221 | biostudies-literature
UnknownRobust Porous WC-Based Self-Supported Ceramic Electrodes for High Current Density Hydrogen Evolution Reaction.
Not available
S-EPMC9130889 | biostudies-literature
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